中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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西北高原生物研究... [224]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Atom-referenced and stabilized soliton microcomb
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2024, 卷号: 67, 期号: 2
作者:
Niu, Rui
;
Wan, Shuai
;
Hua, Tian-Peng
;
Wang, Wei-Qiang
;
Wang, Zheng-Yu
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/17
microcavity
frequency comb
dissipative Kerr solitons
fully stabilized microcomb
ABHD6 drives endocytosis of AMPA receptors to regulate synaptic plasticity and learning flexibility
期刊论文
OAI收割
PROGRESS IN NEUROBIOLOGY, 2024, 卷号: 233, 页码: 17
作者:
Wei, Mengping
;
Yang, Lei
;
Su, Feng
;
Liu, Ying
;
Zhao, Xinyi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/03/25
AMPA receptors
ABHD6
Endocytosis
Synaptic plasticity
Learning flexibility
Discovery and exploration of novel somatostatin receptor subtype 5 (SSTR5) antagonists for the treatment of cholesterol gallstones
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 264, 页码: 16
作者:
Han, Fanghui
;
Zhao, Tingting
;
Zhang, Yanglong
;
Yun, Ying
;
Xu, Yuanyuan
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
SSTR5 antagonist
Gallbladder emptying
Cholesterol gallstones
The temporal effect of uncertain context on the perceptual processing of painful and non-painful stimulation
期刊论文
OAI收割
BIOLOGICAL PSYCHOLOGY, 2024, 卷号: 185, 页码: 11
作者:
Zhuang, Yun
;
Zhao, Ke
;
Fu, Xiaolan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/15
Uncertain context
Pain
Non-painful stimuli
Temporal effect
A novel capsid-XL32-derived adeno-associated virus serotype prompts retinal tropism and ameliorates choroidal neovascularization
期刊论文
OAI收割
BIOMATERIALS, 2024, 卷号: 304, 页码: 13
作者:
Luo, Lin-Lin
;
Xu, Jie
;
Wang, Bing-Qiao
;
Chen, Chen
;
Chen, Xi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/01/26
AAV
Capsid engineering
Phosphosites mutation
Retinal tropism
Neovascularization
New Lupanes from Alstonia scholaris Reducing Uric Acid Level
期刊论文
OAI收割
PLANTA MEDICA, 2024, 卷号: 90, 期号: 1, 页码: 38-46
作者:
Hu, Bin-Yuan
;
Zhao, Yun-Li
;
Xu, Yuan
;
Wang, Xiao-Na
;
Luo, Xiao-Dong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/09
Alstonia scholaris
Apocynaceae
reducing UA levels
lupanes
PENTACYCLIC TRITERPENES
INDOLE ALKALOIDS
LEAVES
Exploring the mechanism of the PTP1B inhibitors by molecular dynamics and experimental study
期刊论文
OAI收割
JOURNAL OF MOLECULAR GRAPHICS & MODELLING, 2023, 卷号: 125, 页码: 12
作者:
Zhao, Tian-Tian
;
Hu, Hao-Jie
;
Gao, Li-Xin
;
Zhou, Yu-Bo
;
Zhu, Yun-Long
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Protein tyrosine phosphatases inhibitors
PTP1B inhibitors
Mechanism study
Molecular dynamics
Physiological and Pathological Functions of TRPM7 Channel and Its Small-molecule Modulators
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 50, 期号: 12, 页码: 2856-2868
作者:
Wang, Yun-Qi
;
Guan, Zi-Yue
;
Gao, Zhao-Bing
;
Zheng, Yue-Ming
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
TRPM7
ion channel
physiological function
disease
small molecule modulators
Diffusion and oxidation behavior of Cr-ZrN coated Zr alloy accident tolerant fuel cladding materials at high temperature
期刊论文
OAI收割
Surface and Coatings Technology, 2023, 期号: 1, 页码: 130246
作者:
Diffusion and oxidation behavior of Cr-ZrN coated Zr alloy accident tolerant fuel cladding materials at high temperature
;
Yining Ding
;
Fen Zhao
;
Panpan Sun
;
Lunlin Shang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/04