中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共105条,第1-10条 帮助

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Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:  
Li, Hongrui;  Liu, Ben-Jin;  Xu, Jiahao;  Song, Shan-Shan;  Ba, Ruixian
  |  收藏  |  浏览/下载:8/0  |  提交时间:2024/08/22
The combination of methionine adenosyltransferase 2A inhibitor and methyltransferase like 3 inhibitor promotes apoptosis of non-small cell lung cancer cells and produces synergistic anti-tumor activity 期刊论文  OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 716, 页码: 12
作者:  
Xuan, Yi-Fei;  Lu, Shan;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan
  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/07/12
Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy 期刊论文  OAI收割
BIOCHEMICAL PHARMACOLOGY, 2024, 卷号: 223, 页码: 17
作者:  
Zhang, Qian;  Wu, Qian;  Huan, Xia-Juan;  Song, Shan -Shan;  Bao, Xu-Bin
  |  收藏  |  浏览/下载:24/0  |  提交时间:2024/06/27
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:  
Wang, Pingyuan;  Zhu, Wen-Ting;  Wang, Yajing;  Song, Shan-Shan;  Xi, Yong
  |  收藏  |  浏览/下载:70/0  |  提交时间:2023/10/17
Proteasome inhibitors reduce CD73 expression partly via decreasing p-ERK in NSCLC cells 期刊论文  OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:  
Su, Ai-Ling;  Tian, Chang-Qing;  Ou, Ying-Jie;  Bao, Xu-Bin;  Huan, Xia-Juan
  |  收藏  |  浏览/下载:22/0  |  提交时间:2023/12/08
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance 期刊论文  OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:  
Wang, Li-Min;  Wang, Pingyuan;  Chen, Xiao-Min;  Yang, Hui;  Song, Shan-Shan
  |  收藏  |  浏览/下载:51/0  |  提交时间:2023/04/10
Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells 期刊论文  OAI收割
MOLECULAR CANCER RESEARCH, 2022, 卷号: 20, 期号: 12, 页码: 1785-1798
作者:  
Sun, Lin;  Wu, Qian;  Huan, Xia-Juan;  Tian, Chang-Qing;  Wang, Ying-Qing
  |  收藏  |  浏览/下载:33/0  |  提交时间:2024/03/21
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:  
Kayumov, Muzaffar;  Jia, Li;  Pardaev, Azizbek;  Song, Shan-Shan;  Mirzaakhmedov, Sharafitdin
  |  收藏  |  浏览/下载:34/0  |  提交时间:2024/03/21
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割
NEOPLASIA, 2022, 卷号: 32, 页码: 12
作者:  
Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin
  |  收藏  |  浏览/下载:28/0  |  提交时间:2023/04/10
Repeated treatments of Capan-1 cells with PARP1 and Chk1 inhibitors promote drug resistance, migration and invasion 期刊论文  OAI收割
CANCER BIOLOGY & THERAPY, 2022, 页码: 14
作者:  
Guo, Ne;  Li, Meng-Zhu;  Wang, Li-Min;  Chen, Hua-Dong;  Song, Shan-Shan
  |  收藏  |  浏览/下载:36/0  |  提交时间:2022/06/15