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Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
A novel approach to water-salt migration prevention: foamed lightweight soil barrier layer technology
期刊论文
OAI收割
COLD REGIONS SCIENCE AND TECHNOLOGY, 2025, 卷号: 236, 页码: 13
作者:
Zhao, Yang
;
Lu, Zheng
;
Liu, Jie
;
Tang, Chuxuan
;
Tabaroei, Abdollah
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/06/27
Saline soil
Water-salt migration
Foamed lightweight soil
Barrier layer
Balmer Decrement and IRX Break in Tracing Dust Attenuation at Scales of Individual Star-forming Regions in NGC 628
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 8
作者:
Qiao, Man
;
Liu, Mingfeng
;
Lyu, Zongfei
;
Liu, Shuang
;
Yang, Chao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/14
(ISM:) dust, extinction
galaxies: ISM
galaxies: individual (NGC 628)
galaxies: star formation
The Influence of the Nuclear Shadowing Effect on Astrophysical Neutrino Flux
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 2
作者:
Liu, Z. Y.
;
Yang, H. Y.
;
Zheng, Y. G.
;
Yang CY(杨初源)
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/04
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/07/28
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
The possible "double-bang firecracker" during a solar prominence eruption
期刊论文
OAI收割
Science China: Physics, Mechanics and Astronomy, 2025, 卷号: 68, 期号: 7
作者:
Zheng, Ruisheng
;
Liu, Yihan
;
Zhong, Ze
;
Zhang, Liang
;
Wang, Xiaoqian
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/10
solar prominence eruptions
coronal mass ejections
coronal pseudostreamers
magnetic reconnecti
The Magnified Waltz: Simulating Light Curves of Binary Stars Passing Through Microcaustics in Strong Lensing Galaxy Clusters
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 987, 期号: 1
作者:
Zheng, Wenwen
;
Fu, Xiaoting
;
Chen, Yang
;
Chen XF(陈雪飞)
;
Guo YJ(郭彦君)
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/07/14