机构

• 长春应用化学研究所 [4]
• 昆明植物研究所 [1]

采集方式

• OAI收割 [5]

内容类型

• 期刊论文 [5]

发表日期

• 2014 [1]
• 2013 [1]
• 2012 [1]
• 2011 [1]
• 2010 [1]

学科主题

筛选

浏览/检索结果: 共5条，第1-5条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Reduced Graphene Oxide Upconversion Nanoparticle Hybrid for Electrochemiluminescent Sensing of a Prognostic Indicator in Early-Stage Cancer 期刊论文  OAI收割 small, 2014, 卷号: 10, 期号: 2, 页码: 330-336 Wu, Li; Wang, Jiasi; Yin, Meili; Ren,Jinsong; Miyoshi,Daisuke; Sugimoto,Naoki; Qu,Xiaogang 收藏  |  浏览/下载：23/0  |  提交时间：2015/03/26 CYCLIN-DEPENDENT KINASES  CELL-CYCLE  ELECTROGENERATED CHEMILUMINESCENCE  FUNCTIONALIZED GRAPHENE  CARBON NANOTUBES  POLYMER BRUSHES  DNA-REPLICATION  BREAST-CANCER  A EXPRESSION  K562 CELLS   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：44/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.   Detection of a Prognostic Indicator in Early-Stage Cancer Using Functionalized Graphene-Based Peptide Sensors 期刊论文  OAI收割 advanced materials, 2012, 卷号: 24, 期号: 1, 页码: 125-131 Feng LY; Wu L; Wang JS; Ren JS; Miyoshi D; Sugimoto N; Qu XG 收藏  |  浏览/下载：14/0  |  提交时间：2013/09/03 WALLED CARBON NANOTUBES  HUMAN CYCLIN A(2)  CELL-CYCLE  NONCOVALENT FUNCTIONALIZATION  PROTEIN MICROARRAYS  CATALYTIC-ACTIVITY  DNA-REPLICATION  K562 CELLS  OXIDE  EXPRESSION   Label-free colorimetric and quantitative detection of cancer marker protein using noncrosslinking aggregation of Au/Ag nanoparticles induced by target-specific peptide probe 期刊论文  OAI收割 biosensors & bioelectronics, 2011, 卷号: 26, 期号: 12, 页码: 4804-4809 Wang XH; Wu L; Ren JS; Miyoshi D; Sugimoto N; Qu XG 收藏  |  浏览/下载：24/0  |  提交时间：2012/06/08 CYCLIN-A EXPRESSION  UNMODIFIED GOLD NANOPARTICLES  SILVER NANOPARTICLES  CELL-PROLIFERATION  MOLECULAR BEACONS  CARBON NANOTUBES  DNA-REPLICATION  K562 CELLS  ASSAY  A(2)   Ultrasensitive and Selective Detection of a Prognostic Indicator in Early-Stage Cancer Using Graphene Oxide and Carbon Nanotubes 期刊论文  OAI收割 advanced functional materials, 2010, 卷号: 20, 期号: 22, 页码: 3967-3971 Wang XH; Wang CY; Qu KG; Song YJ; Ren JS; Miyoshi D; Sugimoto N; Qu XG 收藏  |  浏览/下载：20/0  |  提交时间：2012/04/25 CROSS-CORRELATION SPECTROSCOPY  HUMAN CYCLIN A(2)  CELL-CYCLE  PEPTIDE BEACONS  EPITAXIAL GRAPHENE  MOLECULAR BEACONS  PROTEIN-DETECTION  DNA-REPLICATION  FLUORESCENCE  EXPRESSION