中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
过程工程研究所 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [6]
发表日期
2024 [2]
2017 [1]
2011 [1]
2008 [2]
学科主题
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Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 148, 页码: 15
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Wu, Jianbo
;
Zhang, Ying
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26
Cyclin-dependent kinase 7
Small molecular inhibitor
Triple negative breast cancer
Thieno[3,2-d]pyrimidine derivative
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Discovery of a class of diheteroaromatic amines as orally bioavailable CDK1/4/6 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 23, 页码: 5332-5336
作者:
Fu, Yan
;
Tang, Shuai
;
Su, Yi
;
Lan, Xiaojing
;
Ye, Yan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Cyclin-dependent kinase
CDK inhibitor
Structure-activity relationship
In vitro and in vivo profiling
A protein network-guided screen for cell cycle regulators in Drosophila
期刊论文
OAI收割
BMC SYSTEMS BIOLOGY, 2011, 卷号: 5, 期号: 0, 页码: 文献号: 65
作者:
Guest, Stephen T.
;
Yu, Jingkai
;
Liu, Dongmei
;
Hines, Julie A.
;
Kashat, Maria A.
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2013/11/06
DEPENDENT-KINASE INHIBITOR
RNA INTERFERENCE SCREEN
JAK/STAT SIGNALING COMPONENTS
INFLUENZA-VIRUS REPLICATION
SACCHAROMYCES-CEREVISIAE
TRANSLATION INITIATION
CAENORHABDITIS-ELEGANS
C-ELEGANS
INTERACTOME NETWORK
NTERACTION MAP
Discovery and characterization of a novel inhibitor of CDC25B, LGH00045
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2008, 卷号: 29, 期号: 10, 页码: 1268-1274
作者:
Feng, Xu
;
Wang, Li-na
;
Zhou, Yue-yang
;
Yu, Hai-ping
;
Shen, Qiang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
LGH00045
high-throughput screening
cell division cycle 25B
inhibitor
cyclin-dependent kinase 1
cell circle
discoveryandcharacterizationofanovelinhibitorofcdc25blgh00045
期刊论文
OAI收割
actapharmacologicasinica, 2008, 卷号: 29, 期号: 10, 页码: 1268
作者:
Xu FENG
;
Lina WANG
;
Yueyang ZHOU
;
Haiping YU
;
Qiang SHEN
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
DUAL-SPECIFICITY PHOSPHATASE
HUMAN-CELLS
TRANSGENIC MICE
CANCER
EXPRESSION
CYCLE
TRANSITION
PROGNOSIS
MITOSIS
GROWTH
LGH00045
high-throughput screening
cell division cycle 25B
inhibitor
cyclin-dependent kinase 1
cell circle