机构

• 上海药物研究所 [20]
• 金属研究所 [6]
• 化学研究所 [1]
• 昆明植物研究所 [1]
• 过程工程研究所 [1]
• 高能物理研究所 [1]
• 更多

采集方式

• OAI收割 [31]
• iSwitch采集 [2]

内容类型

• 期刊论文 [33]

发表日期

• 2024 [2]
• 2023 [1]
• 2022 [1]
• 2021 [2]
• 2020 [1]
• 2019 [1]
• 更多

学科主题

• Pharmacolo... [1]

筛选

浏览/检索结果: 共33条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target 期刊论文  OAI收割 NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20 作者:  Wang, Hua;  Tang, Shijie;  Wu, Qibiao;  He, Yayi;  Zhu, Weikang   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/02/28 EGFR-mutant lung cancer  adeno-to-squamous transition  tyrosine kinase inhibitor resistance  transcription factor network  RAPGEF3   Design and Synthesis of Dual Galectin-3 and EGFR Inhibitors Against Liver Fibrosis 期刊论文  OAI收割 CHEMISTRY-AN ASIAN JOURNAL, 2024, 页码: 14 作者:  Liu, Shuanglin;  He, Fei;  Jin, Can;  Li, Qing;  Zhao, Guilong   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/12/25 Galectin-3  EGFR  Inhibitor  Synthesis  Liver fibrosis   Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo 期刊论文  OAI收割 JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162 作者:  Lai, Mengzhen;  Zhang, Tao;  Chen, Hao;  Song, Peiran;  Tong, Linjiang   |  收藏  |  浏览/下载：121/0  |  提交时间：2023/04/10 fourth-generation EGFR inhibitor  EGFRC797S mutation  NSCLC  drug resistance  small molecular inhibitor   Efficient Synthesis and Biological Evaluation of 6-Trifluoroethoxy Functionalized Pteridine Derivatives as EGFR Inhibitors 期刊论文  OAI收割 MEDICINAL CHEMISTRY, 2022, 卷号: 18, 期号: 3, 页码: 353-363 作者:  Lin, Jin;  Zhang, Zemin;  Lin, Xiongqiang;  Chen, Zhendong;  Luc, Tian   |  收藏  |  浏览/下载：37/0  |  提交时间：2022/06/15 Pteridine  derivatives  EGFR  inhibitor  2,2,2-trifluoroethoxy  antitumor activity   Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells 期刊论文  OAI收割 THORACIC CANCER, 2021, 页码: 9 作者:  Zhang, Mi;  Quan, Haitian;  Fu, Li;  Li, Yun;  Fu, Haoyu   |  收藏  |  浏览/下载：65/0  |  提交时间：2021/05/24 EGFR‐  mutant non‐  small cell lung cancer  famitinib  HS‐  10296  multi‐  targeted tyrosine kinase inhibitor  third‐  generation EGFR inhibitor   Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth 期刊论文  OAI收割 BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339 作者:  He,YingYing;  Liu,Shubai;  Newburg,David S.   |  收藏  |  浏览/下载：49/0  |  提交时间：2022/04/02 Trametes versicolor  Cancer stem cell  Tyrosine kinase inhibitor  EGFR  Colorectal cancer  FACTOR RECEPTOR  POLYSACCHAROPEPTIDE  RESISTANCE  TARGET  EGFR  TOOL  PSP  DNA   Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance 期刊论文  OAI收割 MOLECULAR CANCER, 2020, 卷号: 19, 期号: 1, 页码: 15 作者:  Zhang, Tao;  Qu, Rong;  Chan, Shingpan;  Lai, Mengzhen;  Tong, Linjiang   |  收藏  |  浏览/下载：91/0  |  提交时间：2020/07/01 Non-small cell lung cancer (NSCLC)  EGFR T790M  Small-molecule inhibitor  Drug resistance  Ack1   Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFR(L858R/T790M/C797S) 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 6, 页码: 869-873 作者:  Li, Qiannan;  Zhang, Tao;  Li, Shiliang;  Tong, Linjiang;  Li, Junyu   |  收藏  |  浏览/下载：64/0  |  提交时间：2020/07/01 EGFR  mutant  inhibitor  C797S   YL143, a novel mutant selective irreversible EGFR inhibitor, overcomes EGFR(L858R, T790M)-mutant resistance in vitro and in vivo 期刊论文  OAI收割 CANCER MEDICINE, 2018, 卷号: 7, 期号: 4, 页码: 1430-1439 作者:  Zhang, Zhang;  Zou, Jian;  Yu, Lei;  Luo, Jinfeng;  Li, Yan   |  收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08 EGFR inhibitor  lung cancer  pharmacokinetic  selectively  T790M mutation   Identifying egfr-expressed cells and detecting egfr multi-mutations at single-cell level by microfluidic chip 期刊论文  iSwitch采集 Nano-micro letters, 2018, 卷号: 10, 期号: 1, 页码: 10 作者:  Li, Ren;  Zhou, Mingxing;  Li, Jine;  Wang, Zihua;  Zhang, Weikai 收藏  |  浏览/下载：101/0  |  提交时间：2019/04/23 Egfr mutation  Single-cell analysis  Microfluidic chip  Tyrosine kinase inhibitor