中国科学院机构知识库网格系统: 检索

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	Thermococcus Eurythermalis Endonuclease IV Can Cleave Various Apurinic/Apyrimidinic Site Analogues in ssDNA and dsDNA 期刊论文 OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 卷号: 20, 期号: 1, 页码: — 作者: Wang, WW; Zhou, H; Xie, JJ; Yi, GS; He, JH \| 收藏 \| 浏览/下载：57/0 \| 提交时间：2019/12/30 APURINIC APYRIMIDINIC ENDONUCLEASE DOUBLE-STRANDED-DNA ESCHERICHIA-COLI NUCLEOTIDE INCISION EXONUCLEASE-III MAJOR HUMAN ABASIC SITES AP SITES REPAIR BINDING
	Temporal transport of major and trace elements in the upper reaches of the Xijiang River, SW China 期刊论文 OAI收割 Environmental Earth Sciences, 2017, 卷号: 76, 期号: 7 作者: Jing Liu; Si-Liang Li; Jiu-Bin Chen; Jun Zhong; Fu-Jun Yue; Yunchao Lang; Hu Ding \| 收藏 \| 浏览/下载：38/0 \| 提交时间：2018/03/30 Water Geochemistry Temporal Variation Major Ions Trace Elements Human Activity Xijiang River
	Chinese human geography and its contributions SCI/SSCI论文 OAI收割 2016 作者: Fan J. 收藏 \| 浏览/下载：28/0 \| 提交时间：2016/12/16 Chinese human geography main school social contribution land use agricultural zoning point-axis system T-shaped land development structure territorial function major function oriented zone
	Chinese human geography and its contributions SCI/SSCI论文 OAI收割 2016 作者: Fan J. \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2017/11/09 Chinese human geography main school social contribution land use agricultural zoning point-axis system T-shaped land development structure territorial function major function oriented zone
	Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文 OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者: Zeng, Guang-Zhi; Fan, Jun-Ting; Xu, Jun-Ju; Li, Yan; Tan, Ning-Hua 收藏 \| 浏览/下载：41/0 \| 提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA) one of the major components isolated from the traditional Chinese medicine Rubia yunnanensis exhibited inhibitory activity on the proliferation of several human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle arrest in human cervical carcinoma HeLa cells. Further MTA was found to induce apoptosis of HeLa cells through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and release of cytochrome c into the cytosol which caused the cleavage of caspase and poly(ADP-ribose) polymerase and finally triggered the apoptosis. Furthermore the p53/p21/Cdc2-cyclin B1 signaling was found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of R. yunnanensis a folk anti-cancer herb used in Yunnan China.
	Major ion chemistry and dissolved inorganic carbon cycling in a human-disturbed mountainous river (the Luodingjiang River) of the Zhujiang (Pearl River), China 期刊论文 OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2009, 卷号: 407, 期号: 8, 页码: 2796-2807 作者: Zhang, Shurong; Lu, X. X.; Sun, Huiguo; Han, Jingtai; Higgitt, David Laurence \| 收藏 \| 浏览/下载：17/0 \| 提交时间：2018/09/26 Major ions Dissolved inorganic carbon Water chemistry Human impacts Stable carbon isotope Zhujiang (Pearl River)
	Major ion chemistry and dissolved inorganic carbon cycling in a human-disturbed mountainous river (the Luodingjiang River) of the Zhujiang (Pearl River), China 期刊论文 OAI收割 SCIENCE OF THE TOTAL ENVIRONMENT, 2009, 卷号: 407, 期号: 8, 页码: 2796-2807 作者: Zhang, Shurong; Lu, X. X.; Sun, Huiguo; Han, Jingtai; Higgitt, David Laurence \| 收藏 \| 浏览/下载：31/0 \| 提交时间：2018/09/26 Major ions Dissolved inorganic carbon Water chemistry Human impacts Stable carbon isotope Zhujiang (Pearl River)