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	Systems Signatures Reveal Unique Remission-path of Type 2 Diabetes Following Roux-en-Y Gastric Bypass Surgery 期刊论文 OAI收割 EBIOMEDICINE, 2018, 卷号: 28, 期号: 1, 页码: 234-240 作者: Li, Qing-Run; Wang, Zi-Ming; Wang, Dan-Dan; Su, Zhi-Duan; Gao, Xian-Fu \| 收藏 \| 浏览/下载：49/0 \| 提交时间：2019/04/28 Branched-chain Sleeve Gastrectomy Glucose-metabolism Insulin-resistance Glycemic Control Edge Biomarkers Weight-loss Bile-acids Individuals Sensitivity
	Improvement of Adenosylcobalamin Production by Metabolic Control Strategy in Propionibacterium freudenreichii 期刊论文 OAI收割 APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2012, 卷号: 167, 期号: 1, 页码: 62-72 作者: Wang, Peng; Wang, Yunshan; Su, Zhiguo 收藏 \| 浏览/下载：24/0 \| 提交时间：2013/10/17 Biosynthesis Adenosylcobinamide Metabolism control 5 Propionibacterium freudenreichii 6-Dimethylbenzimidazole
	PID control of glucose concentration in subjects with type 1 diabetes based on a simplified model: An in silico trial (EI CONFERENCE) 会议论文 OAI收割 10th World Congress on Intelligent Control and Automation, WCICA 2012, July 6, 2012 - July 8, 2012, Beijing, China 作者: Yu L. 收藏 \| 浏览/下载：29/0 \| 提交时间：2013/03/25 An artificial pancreas system (APS) mimics the function of a real pancreas through monitoring a diabetic's blood glucose and administering the right dose of insulin via an automatic control loop. It is hailed as a promising cure of diabetes though this technology is still years away from commercial use due to a few technological bottlenecks. The simulation model of insulin-glucose metabolism of type 1 diabetes mellitus (T1DM) is an essential part of APS. In order to simplify the parameter identification task so that the model can be implemented electronically with ease this paper presents a simplified model based on Routh approximation model reduction method. The results show that the approximation error between the simplified model and the original model is so small that can be neglected. Based on the simplified model a PID controller is designed to maintain normoglycemia (90mg/dl) in subjects with T1DM. The in silico simulation results show that the glucose concentration is controlled well the risk of hyperglycemia and hypoglycemia is reduced a lot. This suggests that the simplified model describes the insulin-glucose metabolism process accurately and the PID control algorithm is well-suitable to guide the further development of an APS. 2012 IEEE.
	TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation 期刊论文 OAI收割 JOURNAL OF LIPID RESEARCH, 2009, 卷号: 50, 期号: 6, 页码: 1057-1067 作者: Lei, L; Xiong, Y; Chen, J; Yang, JB; Wang, Y 收藏 \| 浏览/下载：48/0 \| 提交时间：2015/07/22 atherosclerosis cholesterol esterification inflammatory cytokine lipid metabolism transcription control
	液相色谱应用于复方中药药效物质基础研究学位论文 OAI收割博士: 中国科学院研究生院, 2008 汤浩收藏 \| 浏览/下载：50/0 \| 提交时间：2013/04/27 复方中药药效物质基础高效液相色谱赤栀黄方剂药物代谢酶P450 质量控制 Compound traditional Chinese medicine (compound TCM) Therapeutic basis High performance liquid chromatography (HPLC) Chi-Zhi-HuangDecoction (PGR) Drug metabolism enzyme P450 (CYP) Quality control