中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
计算技术研究所 [2]
上海药物研究所 [2]
长春光学精密机械与物... [1]
心理研究所 [1]
采集方式
OAI收割 [6]
内容类型
期刊论文 [5]
会议论文 [1]
发表日期
2024 [2]
2023 [1]
2020 [1]
2014 [1]
2010 [1]
学科主题
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D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 3, 页码: 10
作者:
Shi, Yulong
;
Li, Chongwu
;
Zhang, Xinben
;
Peng, Cheng
;
Sun, Peng
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2024/05/07
lung cancer
EGFR mutation
drug sensitivity prediction
patient case database
deep learning
Single-sequence protein structure prediction by integrating protein language models
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2024, 卷号: 121, 期号: 13, 页码: 7
作者:
Jing, Xiaoyang
;
Wu, Fandi
;
Luo, Xiao
;
Xu, Jinbo
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/05/20
protein structure prediction
protein language model
single-sequence protein structure rediction
antibody structure prediction
single mutation effect
Histopathological bladder cancer gene mutation prediction with hierarchical deep multiple-instance learning
期刊论文
OAI收割
MEDICAL IMAGE ANALYSIS, 2023, 卷号: 87, 页码: 13
作者:
Yan, Rui
;
Shen, Yijun
;
Zhang, Xueyuan
;
Xu, Peihang
;
Wang, Jun
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/12/04
Bladder cancer
Contrastive learning
Gene mutation prediction
Histopathological image analysis
Multiple instance learning
Identification of a missense ARSA mutation in metachromatic leukodystrophy and its potential pathogenic mechanism
期刊论文
OAI收割
MOLECULAR GENETICS & GENOMIC MEDICINE, 2020, 页码: 11
作者:
Guo, Liyuan
;
Jin, Bo
;
Zhang, Yidan
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/10/22
ARSA gene mutation
bioinformatics analysis
expression profiling
Metachromatic leukodystrophy
mutation effect prediction
Molecular Dynamics and Bioactivity of a Novel Mutated Human Parathyroid Hormone
期刊论文
OAI收割
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH, 2014, 卷号: 13, 期号: 4, 页码: 511-518
作者:
Jiang, Yueshui
;
Gu, Jiande
;
Lei, Jianyong
;
Chen, Yun
;
Jin, Jian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Parathyroid hormone
Mutation prediction
Molecular dynamics
RANKL/OPG
UAMS-32P cell
The costs prediction of AOD furnace based on improved RBF neural network (EI CONFERENCE)
会议论文
OAI收割
2010 International Conference on Computer, Mechatronics, Control and Electronic Engineering, CMCE 2010, August 24, 2010 - August 26, 2010, Changchun, China
Na T.
;
Zhang D.-J.
;
Hui L.
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2013/03/25
In order to predict the cost
a model of cost prediction was set up based on adaptive hierarchical genetic algorithm and RBF neural network. Hierarchical genetic algorithm could optimize the topology and the parameters simultaneously. Compared with simple genetic algorithm
it has more efficiency in not only accelerating and stabilizing the parameters training but also determining the structure of the network. Adaptive crossover and mutation probability could accelerate the speed and avoid prematurity. The model was tested by five samples. The results showed that the prediction model has high prediction accuracy
which indicated that it was applicable to predict the cost by the model. 2010 IEEE.