机构

• 上海药物研究所 [5]
• 合肥物质科学研究院 [3]

采集方式

• OAI收割 [8]

内容类型

• 期刊论文 [8]

发表日期

• 2025 [1]
• 2024 [1]
• 2023 [1]
• 2022 [1]
• 2021 [3]
• 2020 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共8条，第1-8条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy 期刊论文  OAI收割 ADVANCED MATERIALS, 2025, 页码: 13 作者:  Jiang, Xingyu;  Lai, Yi;  Xia, Wenzheng;  Yang, Wenfang;  Wang, Junjue   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/04/24 acid-activatable photodynamic therapy  double-layered microneedle  glioblastoma therapy  light-activatable PROTAC prodrug  protein degradation   An overview of PROTACs targeting MDM2 as a novel approach for cancer therapy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 272, 页码: 8 作者:  Li, Huiwen;  Cai, Xinhui;  Yang, Xiaoyu;  Zhang, Xuan   |  收藏  |  浏览/下载：27/0  |  提交时间：2024/09/26 MDM2  PROTAC  p53  MDMX  Targeted protein degradation   Stimuli-activatable PROTACs for precise protein degradation and cancer therapy 期刊论文  OAI收割 SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085 作者:  Gao, Jing;  Yang, Lei;  Lei, Shumin;  Zhou, Feng;  Nie, Huijun   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 PROTAC  Stimuli-activatable prodrug  Precise protein degradation  Nanomedicine  Combinatory therapy   Key Considerations in Targeted Protein Degradation Drug Discovery and Development 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2022, 卷号: 10 作者:  Qin, Liena;  Dai, Han;  Wang, Junfeng   |  收藏  |  浏览/下载：41/0  |  提交时间：2022/12/23 targeted protein degradation  PROTAC  molecular glue  chemically induced proximity  drug discovery and development   Protein degradation technology: a strategic paradigm shift in drug discovery 期刊论文  OAI收割 JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 卷号: 14 作者:  Li, Haobin;  Dong, Jinyun;  Cai, Maohua;  Xu, Zhiyuan;  Cheng, Xiang-Dong   |  收藏  |  浏览/下载：29/0  |  提交时间：2021/11/01 Protein degradation  Degradation pathway  Degradation technology  PROTAC  Monomeric degraders   PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12 作者:  Qi, Si-Min;  Dong, Jinyun;  Xu, Zhi-Yuan;  Cheng, Xiang-Dong;  Zhang, Wei-Dong   |  收藏  |  浏览/下载：40/0  |  提交时间：2021/06/15 PROTAC  E3 ubiquitin ligase  protein degradation  ubiquitin-proteasome system  cancer therapy   Drug design targeting active posttranslational modification protein isoforms 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2021, 卷号: 41, 期号: 3, 页码: 1701-1750 作者:  Meng, Fanwang;  Liang, Zhongjie;  Zhao, Kehao;  Luo, Cheng   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/22 Allosteric Inhibitor  Covalent Inhibitor  Posttranslational Modifications  Precision Medicine  Protac Protein Degradation  Protein‐  Protein Interactions  Ptm Protein Isoforms  Rational Drug Design   Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14 作者:  Zhang, Xin;  Xu, Fang;  Tong, Linjiang;  Zhang, Tao;  Xie, Hua   |  收藏  |  浏览/下载：82/0  |  提交时间：2020/07/01 Epidermal growth factor receptor (EGFR)  Resistance  Proteolysis targeting chimera (PROTAC)  Protein degradation