中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [10]
上海生物化学与细胞生... [5]
金属研究所 [3]
地理科学与资源研究所 [3]
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生态环境研究中心 [2]
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OAI收割 [31]
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期刊论文 [30]
学位论文 [1]
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2025 [1]
2023 [3]
2020 [4]
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Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
Study on p-y curve of large diameter pile under long-term cyclic loading
期刊论文
OAI收割
APPLIED OCEAN RESEARCH, 2023, 卷号: 140, 页码: 11
作者:
Xiao-ling, Zhang
;
Rui, Zhou
;
Yan, Han
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/29
Large diameter pile foundation
Long -term cyclic loading
Ultimate soil resistance
Corrected p -y curve
Research on dynamic p-y curves in liquefied sand under cyclic loading conditions
期刊论文
OAI收割
OCEAN ENGINEERING, 2023, 卷号: 285, 页码: 7
作者:
Zhang, Xiao-ling
;
Zhang, Bing-jie
;
Zhang, Wen-Xi
;
Han, Yan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/09
Dynamic p -y curve
Cyclic loads
Pore pressure ratio
Soil resistance around the pile
A corrected p-y curve model for large-diameter pile foundation of offshore wind turbine
期刊论文
OAI收割
OCEAN ENGINEERING, 2023, 卷号: 273, 页码: 114012
作者:
Zhang, Xiao-ling
;
Zhou, Rui
;
Zhang, Guo-liang
;
Han, Yan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/04
Offshore wind turbine
Large diameter pile
Size effect
P -y curve model
The pile -soil interaction
Pharmacokinetics, mass balance, and metabolism of [C-14]vicagrel, a novel irreversible P2Y(12) inhibitor in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Zheng, Yuan-dong
;
Zhang, Hua
;
Zhan, Yan
;
Bian, Yi-cong
;
Ma, Sheng
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2021/05/24
vicagrel
[C-14]vicagrel
vicagrel pharmacokinetics
vicagrel metabolism
mass balance
P2Y(12) receptor inhibitor
Possible Tricritical Behavior and Anomalous Lattice Softening in van der Waals Itinerant Ferromagnet Fe(3)GeTe(2)under High Pressure
期刊论文
OAI收割
CHINESE PHYSICS LETTERS, 2020, 卷号: 37
作者:
Xu, Jie-Min
;
Wang, Shu-Yang
;
Wang, Wen-Jun
;
Zhou, Yong-Hui
;
Chen, Xu-Liang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/10/26
62
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20
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72
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钯基催化剂上 1 ,2 二氯苯催化降解过程及机理研究
学位论文
OAI收割
北京: 中国科学院生态环境研究中心, 2020
作者:
李娜
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/07/06
催化降解 1,2 二氯苯,副产物分布,多氯有机化合物,反应机理
Catalytic DegradatIon 1,2 d Ichlorobenzene b y Products DistributIon p Olychlorinated Organic Compounds r Eact Ion Mechanism
Impacts of CYP2C19 genetic polymorphisms on bioavailability and effect on platelet adhesion of vicagrel, a novel thienopyridine P2Y12inhibitor
期刊论文
OAI收割
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2020, 卷号: 86, 期号: 9, 页码: 1860-1874
作者:
Zhang, Yifan
;
Zhu, Xiaoxue
;
Zhan, Yan
;
Li, Xiaojiao
;
Liu, Cai
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/21
P2Y(12)inhibitor
pharmacodynamics
pharmacokinetics
vicagrel
Pharmacokinetics and pharmacokinetic/pharmacodynamic relationship of vicagrel, a novel thienopyridine P2Y(12) inhibitor, compared with clopidogrel in healthy Chinese subjects following single oral dosing
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 卷号: 127, 页码: 151-160
作者:
Li, Cai
;
Zhang, Yifan
;
Chen, Weili
;
Lu, Youming
;
Li, Wei
  |  
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2019/01/08
Vicagrel
Clopidogrel
P2Y(12) inhibitor
Pharmacokinetics
Active metabolite
Thienopyridine
Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y(1) receptor antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 302-310
作者:
Peng, Jingjing
;
Zhao, Lifen
;
Wang, Lanlan
;
Chen, Hui
;
Qiu, Yunguang
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/01/08
P2Y(1) receptor antagonist
2-(phenoxyaryl)-3-urea derivatives
Anti-Platelet