机构

• 上海药物研究所 [3]
• 金属研究所 [2]

采集方式

• OAI收割 [5]

内容类型

• 期刊论文 [5]

发表日期

• 2019 [1]
• 2018 [1]
• 2013 [2]
• 2010 [1]

学科主题

筛选

浏览/检索结果: 共5条，第1-5条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Molecular Mechanism of Binding Selectivity of Inhibitors toward BACE1 and BACE2 Revealed by Multiple Short Molecular Dynamics Simulations and Free-Energy Predictions 期刊论文  OAI收割 ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 10, 页码: 4303-4318 作者:  Chen, Jianzhong;  Wang, Jinan;  Yin, Baohua;  Pang, Laixue;  Wang, Wei   |  收藏  |  浏览/下载：111/0  |  提交时间：2020/07/01 beta-amyloid cleaving enzyme  binding selectivity  MSMD  hierarchical clustering analysis  MM-GBSA   Effect of microenvironment on beta-site amyloid precursor protein cleaving enzyme 1 expression in PC12 Cells 期刊论文  OAI收割 Journal of Shanghai Jiaotong University .Medical Science, 2018, 卷号: 38, 期号: 9, 页码: 1005-1012 作者:  Yang Huanqing;  He Xiang;  Du Xiaoguang;  Xiao Shifu;  Wang Tao   |  收藏  |  浏览/下载：141/0  |  提交时间：2019/01/08 Alzheimer's disease  microenvironment  PC12 cell  beta-site amyloid precursor protein cleaving enzyme 1 (BACE1)  amyloid-beta peptide (Abeta)   Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：22/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2013, 卷号: 45, 期号: 8, 页码: 613-621 作者:  Li Xiaoman;  Hong Lin;  Coughlan Kathleen;  Wang Liang;  Cao Liu   |  收藏  |  浏览/下载：16/0  |  提交时间：2021/02/02 AMYLOID PRECURSOR PROTEIN  BETA-SECRETASE BACE1  GATED SODIUM-CHANNELS  CLEAVING ENZYME  GGA PROTEINS  ASPARTYL PROTEASE  NEURONAL-ACTIVITY  GENETIC DELETION  CYTOSOLIC DOMAIN  ALPHA-SECRETASE  memapsin 2  BACE1  beta-amyloid  subsite specificity  activity prediction   2,2',4'-Trihydroxychalcone from Glycyrrhiza glabra as a new specific BACE1 inhibitor efficiently ameliorates memory impairment in mice 期刊论文  OAI收割 JOURNAL OF NEUROCHEMISTRY, 2010, 卷号: 114, 期号: 2, 页码: 374-385 作者:  Zhu, Zhiyuan;  Li, Chenjing;  Wang, Xu;  Yang, Zhengyi;  Chen, Jing   |  收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Alzheimer's disease  amyloid-beta  inhibitor  transgenic mice  trihydroxychalcone  beta-site amyloid precursor protein-cleaving enzyme 1 (beta-secretase)