机构

• 上海药物研究所 [28]
• 上海生物化学与细胞生... [1]
• 兰州化学物理研究所 [1]

采集方式

• OAI收割 [30]

内容类型

• 期刊论文 [28]
• 会议论文 [2]

发表日期

• 2025 [4]
• 2024 [4]
• 2023 [2]
• 2022 [6]
• 2021 [4]
• 2019 [4]
• 更多

学科主题

• Biochemist... [1]
• 分析化学与药物化学 [1]

筛选

浏览/检索结果: 共30条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Covalent sortase A inhibitor, α, β-unsaturated aldehydes, prevents Staphylococcus aureus infection 期刊论文  OAI收割 MICROBIAL PATHOGENESIS, 2025, 卷号: 204, 页码: 12 作者:  Wang, Jianchao;  He, Yuan;  Chu, Chenliang;  Wu, Ziqi;  Zhang, Ting   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/06/23 Sortase A  Covalent inhibitor  alpha  beta-unsaturated aldehydes  Anti-virulence therapy  Staphylococcus aureus   Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects In Vivo 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9 作者:  Wu, Hengbo;  Lai, Gan-Qiang;  Cheng, Ruixiang;  Huang, Hui;  Wang, Ju   |  收藏  |  浏览/下载：1/0  |  提交时间：2025/04/24 RNA epigenetics  N(6)-methyladenosine  ALKBH5  covalent inhibitor  antileukemia   In vitro and In vivo Drug Metabolism Analysis of BPI-460372-A Covalent TEAD1/3/4 Inhibitor 期刊论文  OAI收割 CURRENT DRUG METABOLISM, 2025, 页码: 15 作者:  Liu, Xiaoyun;  Zhong, Dafang;  Tang, Chongzhuang;  Xu, Xiaofeng;  Lan, Hong   |  收藏  |  浏览/下载：0/0  |  提交时间：2025/04/24 Hippo signaling pathway  TEAD inhibitor  covalent inhibitor  BPI-460372  UHPLC-Orbitrap-HRMS  cysteine  S-conjugate beta-lyase.   Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16 作者:  Tang, Cai-ling;  Li, Yuan-qing;  Du, Xi-kun;  Fang, Xiao-xia;  Guang, Yi-man   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01 dynamics simulation  CECR2  covalent inhibitor  allosteric effect   Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20 作者:  Luo, Menglan;  Ye, Yunfei;  Tang, Lu;  Kan, Weijuan;  Chen, Lin   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/11/26 Menin  Covalent inhibitor  Antitumor  Degradation   DNA-Encoded Noncanonical Substrate Library for Protease Profiling 期刊论文  OAI收割 CHEMBIOCHEM, 2024, 页码: 12 作者:  Zhang, Huiya;  Xing, Yuyu;  Yang, Yixuan;  Tang, Bixi;  Zong, Zhaoyun   |  收藏  |  浏览/下载：79/0  |  提交时间：2024/12/16 Protease substrate  DNA-encoded library  Combinatorial peptide library  High-throughput screening  Covalent inhibitor  Noncanonical peptide   Identification of benzo[ b ]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 146, 页码: 15 作者:  Cao, Xin-Yu;  Li, Xinge;  Wang, Feng;  Duan, Yichen;  Wu, Xingmei   |  收藏  |  浏览/下载：34/0  |  提交时间：2024/06/27 Serine synthesis pathway  PHGDH  Stattic  Covalent inhibitor  Antitumor   Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16 作者:  Sun, Yaoliang;  Chen, Zhiwen;  Liu, Guobin;  Chen, Xiaoai;  Shi, Zihan   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/25 Inhibitor  Cancer  Threonine tyrosine kinase (TTK)  Covalent   Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10 作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 NPAS3  Covalent inhibitor  Protein -protein interaction  5-nitrothiazole warhead   Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay