中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
金属研究所 [3]
海洋研究所 [1]
自动化研究所 [1]
上海生物化学与细胞生... [1]
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OAI收割 [13]
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Euphornin L promotes lipid clearance by dual regulation of LDLR and PCSK9
期刊论文
OAI收割
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2021, 卷号: 22, 期号: 6, 页码: 9
作者:
Li, Huihui
;
Li, Jun
;
Zhang, Xianjing
;
Li, Jiaomeng
;
Xi, Cong
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
euphornin L
lipid-lowering activity
low density lipoprotein receptor
proprotein convertase subtilisin
kexin type 9
extracellular signal-regulated kinase protein
secretion
Design, synthesis, and biological evaluation of novel tetrahydroprotoberberine derivatives (THPBs) as proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators for the treatment of hyperlipidemia
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 6, 页码: 1216-1230
作者:
Wu, Chenglin
;
Xi, Cong
;
Tong, Junhua
;
Zhao, Jing
;
Jiang, Hualiang
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
designsynthesisandbiologicalevaluationofnoveltetrahydroprotoberberinederivativesthpbsasproproteinconvertasesubtilisinkexintype9pcsk9modulatorsforthetreatmentofhyperlipidemia
期刊论文
OAI收割
actapharmaceuticasinicab, 2019, 卷号: 9, 期号: 6, 页码: 1216
作者:
Wu Chenglin
;
Xi Cong
;
Tong Junhua
;
Zhao Jing
;
Jiang Hualiang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/07/01
DOPAMINE D-1
BERBERINE
EXPRESSION
INHIBITORS
IDENTIFICATION
CHOLESTEROL
MUTATIONS
LDLR
PCSK9
Tetrahydroprotoberberine derivatives
Low-density lipoprotein cholesterol
Lipid-lowering
PCSK9 expression
Low-density lipoprotein receptor
Total cholesterol
Hyperlipidemia hamster
An Innovation for Treating Orthotopic Pancreatic Cancer by Preoperative Screening and Imaging-Guided Surgery
期刊论文
OAI收割
Molecular Imaging And Biology, 2018, 期号: x, 页码: x
作者:
Ziyu Han
;
Wenting Shang
;
Xiaoyuan Liang
;
Hao Yan
;
Min Hu
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2018/10/10
Low-density Lipoprotein Receptor (Ldlr)
Photoacoustic Imaging
Peptide-22
Optical-guided Surgery
A low-density lipoprotein receptor-related protein (LRP)-like molecule identified from Chlamys farreri participated in immune response against bacterial infection
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2014, 卷号: 36, 期号: 2, 页码: 336-343
作者:
Liu, Rui
;
Wang, Lingling
;
Sun, Ying
;
Wang, Leilei
;
Zhang, Huan
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2015/06/11
Chlamys farreri
Low-density lipoprotein receptor-related
protein (LRP)
Innate immunity
Ligands binding
Antimicrobial activity
Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex
期刊论文
OAI收割
GENES & DEVELOPMENT, 2013, 卷号: 27, 期号: 21, 页码: 2305-2319
作者:
Ke, Jiyuan
;
Harikumar, Kaleeckal G.
;
Erice, Clara
;
Chen, Chen
;
Gu, Xin
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Norrin structure
cystine knot growth factor
Wnt/beta-catenin signaling
Frizzled 4
low-density lipoprotein receptor-related protein 5/6
tetraspanin 12
The proteasome inhibitor MG132 enhances LDL uptake in hepatocytes through regulating LDLR and PCSK9 expression: a novel role in cholesterol homeostasis
会议论文
OAI收割
作者:
Yan, Hong
;
Ma, Yan-ling
;
Wang, Xin-bo
;
Gui, Yu-zhou
;
Gao, Fei
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/01/08
Low-density lipoprotein receptor
proprotein convertase subtilisin/kexin type 9
protein kinase C
hamster
Sleeve gastrectomy prevents lipoprotein receptor-1 expression in aortas of obese rats
期刊论文
OAI收割
WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 卷号: 17, 期号: 32, 页码: 3739-3744
作者:
Bai Jie
;
Wang Yong
;
Liu Yuan
;
Geng DongHua
;
Liu JinGang
  |  
收藏
  |  
浏览/下载:165/0
  |  
提交时间:2021/02/02
LOW-DENSITY-LIPOPROTEIN
OXIDIZED LDL RECEPTOR-1
VASCULAR ENDOTHELIAL-CELLS
WEIGHT-LOSS
BLOOD-PRESSURE
GASTRIC BYPASS
LONG-TERM
HYPERTENSION
LOX-1
WOMEN
Sleeve gastrectomy
Morbid obesity
High fat diet
Aorta
Lipoprotein receptor-1 expression
Sleeve gastrectomy prevents lipoprotein receptor-1 expression in aortas of obese rats
期刊论文
OAI收割
WORLD JOURNAL OF GASTROENTEROLOGY, 2011, 卷号: 17, 期号: 32, 页码: 3739-3744
作者:
Bai Jie
;
Wang Yong
;
Liu Yuan
;
Geng DongHua
;
Liu JinGang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/02/02
LOW-DENSITY-LIPOPROTEIN
OXIDIZED LDL RECEPTOR-1
VASCULAR ENDOTHELIAL-CELLS
WEIGHT-LOSS
BLOOD-PRESSURE
GASTRIC BYPASS
LONG-TERM
HYPERTENSION
LOX-1
WOMEN
Sleeve gastrectomy
Morbid obesity
High fat diet
Aorta
Lipoprotein receptor-1 expression
Globular adiponectin protects human umbilical vein endothelial cells against apoptosis through adiponectin receptor 1/adenosine monophosphate-activated protein kinase pathway
期刊论文
OAI收割
CHINESE MEDICAL JOURNAL, 2011, 卷号: 124, 期号: 16, 页码: 2540-2547
作者:
Zhao Hongyu
;
Zhao Min
;
Yi Tongning
;
Zhang Jin
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2021/02/02
CORONARY-ARTERY-DISEASE
FATTY-ACID OXIDATION
GLUCOSE ENHANCES APOPTOSIS
LOW-DENSITY-LIPOPROTEIN
DIABETIC MICE
UP-REGULATION
MUSCLE-CELLS
EXPRESSION
MACROPHAGES
SUPPRESSION
globular adiponectin
adiponectin receptor 1
AMP-activated protein kinase
apoptosis
intermittent glucose