中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [8]
合肥物质科学研究院 [2]
采集方式
OAI收割 [10]
内容类型
期刊论文 [10]
发表日期
2024 [1]
2023 [1]
2022 [2]
2020 [1]
2017 [5]
学科主题
筛选
浏览/检索结果:
共10条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Design, synthesis, and biological evaluation of pyrido[2,3-d]pyrimidin-7 (8H)-one derivatives as potent USP1 inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Li, Hongrui
;
Liu, Ben-Jin
;
Xu, Jiahao
;
Song, Shan-Shan
;
Ba, Ruixian
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/08/22
USP1 inhibitor
Structure -activity relationships
Olaparib-resistant cell
Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2023, 页码: 24
作者:
Wang, Li-Min
;
Wang, Pingyuan
;
Chen, Xiao-Min
;
Yang, Hui
;
Song, Shan-Shan
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/04/10
homologous recombination repair
olaparib-resistant
PARP inhibitor
PARP7
type I interferons
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:
Kayumov, Muzaffar
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/03/21
PARP1
Olaparib
Alantolactone
Syntheticlethality
BRCA1/2mutant
Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial
期刊论文
OAI收割
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:
Liu, Jihong
;
Yin, Rutie
;
Wu, Lingying
;
Zhu, Jianqing
;
Lou, Ge
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2022/05/05
BRCA mutation
China
olaparib
ovarian cancer
PARP inhibitor
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
OAI收割
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:
Chen, Wen-hua
;
Song, Shan-shan
;
Qi, Ming-hui
;
Huan, Xia-juan
;
Wang, Ying-qing
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
Combining 53BP1 with BRCA1 as a biomarker to predict the sensitivity of poly(ADP-ribose) polymerase (PARP) inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 7, 页码: 1038-1047
作者:
Yang, Zhong-min
;
Liao, Xue-mei
;
Chen, Yi
;
Shen, Yan-yan
;
Yang, Xin-ying
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
homologous recombination repair defects
breast cancer
ovarian cancer
TALEN
combined biomarker
simmiparib
olaparib
Poly(ADP-ribose)polymerase (PARP) inhibition and anticancer activity of simmiparib, a new inhibitor undergoing clinical trials
期刊论文
OAI收割
CANCER LETTERS, 2017, 卷号: 386, 页码: 47-56
作者:
Yuan, Bo
;
Ye, Na
;
Song, Shan-Shan
;
Wang, Yu-Ting
;
Song, Zilan
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Homologous recombination repair defects
Olaparib
Growth inhibition
Patient-derived xenografts
Pharmacokinetics
combining53bp1withbrca1asabiomarkertopredictthesensitivityofpolyadpribosepolymeraseparpinhibitors
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 7, 页码: 1036
作者:
Yang Zhongmin
;
Liao Xuemei
;
Chen Yi
;
Shen Yanyan
;
Yang Xinying
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
homologous recombination repair defects
breast cancer
ovarian cancer
TALEN
combined biomarker
simmiparib
olaparib
discoveryofpotent24difluorolinkerpolyadpribosepolymerase1inhibitorswithenhancedwatersolubilityandinvivoanticancerefficacy
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1521
作者:
Chen Wenhua
;
Song Shanshan
;
Ql Minghui
;
Huan Xiajuan
;
Wang Yingqing
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
PARP INHIBITORS
MEDICINAL CHEMISTRY
DRUG DISCOVERY
CANCER
THERAPY
DESIGN
FLUORINE
SUCCESS
PREDICT
METRICS
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors