中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
大连化学物理研究所 [4]
过程工程研究所 [2]
昆明植物研究所 [1]
生态环境研究中心 [1]
烟台海岸带研究所 [1]
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OAI收割 [15]
内容类型
期刊论文 [15]
发表日期
2023 [1]
2022 [1]
2020 [1]
2018 [1]
2010 [2]
2008 [1]
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学科主题
Biochemist... [1]
Chemistry [1]
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Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:
Munikishore,Rachakunta
;
Liu,Rui
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Nian,Yin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/07/22
Buxus alkaloid
Structural modification
T -type calcium channel
Analgesic activity
Docking analysis
Structure -activity relationship study
BUXOZINE-C
SEMPERVIRENS
RING
CONSTITUTION
Relationship Between the Structure and Immune Activity of Components From the Active Polysaccharides APS-II of Astragali Radix by Enzymolysis of Endo alpha-1,4-Glucanase
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 15
作者:
Li, Ke
;
Li, Xue-qin
;
Li, Guang-xin
;
Cui, Lian-jie
;
Qin, Xue-mei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
APS-II
enzymolysis
structure analysis
immune activity
structure-activity relationship
Structural Modifications of the Triazolo-thiadiazole Derivatives as DOT1L Inhibitors and Their Activities
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2020, 卷号: 40, 期号: 5, 页码: 1345-1354
作者:
Xu Xiaoming
;
Guo Siqi
;
Zhang Jing
;
Chen Yantao
;
Kang Yaqing
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/12/24
DOT1L inhibitor
ttriazolo-thiadiazole
structural modification
hydrophobic substituent
structure-activity analysis
Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity
期刊论文
OAI收割
MARINE DRUGS, 2018, 卷号: 16, 期号: 3
作者:
Liu, Jin
;
Chen, Yu
;
Li, Jing-Ya
;
Luo, Cheng
;
Li, Jia
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
phidianidine
marine natural products
PTP1B inhibitor
specific selectivity
docking analysis
Function Oriented Synthesis
structure-activity relationship
Three-Dimensional Quantitative Structure-Activity Relationships of flavonoids and estrogen receptors based on docking
期刊论文
OAI收割
CHINESE SCIENCE BULLETIN, 2010, 卷号: 55, 期号: 15, 页码: 1488-1494
作者:
Wu Yang
;
Wang Yong
;
Zhang AiQian
;
Yu HongXia
;
Wang LianSheng
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
flavonoids
ligand-receptor docking
Three-Dimensional Quantitative Structure Activity Relationship (3D-QSAR)
comparative molecular field analysis (CoMFA)
molecular similarity index analysis (CoMSIA)
Three-dimensional quantitative structure activity relationship of flavonoids and estrogen receptor based on docking
期刊论文
OAI收割
Chinese Science Bulletin, 2010, 卷号: 55, 期号: 2, 页码: 132-139
作者:
Wu Yang
;
Wang Yong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
(3D-QSAR)
(CoMFA)
(CoMSIA)
flavonoids
ligand-receptor docking
three-dimensional quantitative structure activity relationship(3D-QSAR)
comparative molecular field analysis(CoMFA)
molecular similarity index analysis(CoMSIA)
Modeling resistance index of taxoids to MCF-7 cell lines using ANN together with electrotopological state descriptors
期刊论文
OAI收割
acta pharmacologica sinica, 2008, 卷号: 29, 期号: 3, 页码: 385-396
作者:
Dong, Pei-pei
;
Zhang, Yan-yan
;
Ge, Guang-bo
;
Ai, Chun-zhi
;
Liu, Yong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2010/11/30
artificial neural network model
taxoids
multidrug resistance
resistance index
electrotopological state indices
principle component analysis
quantitative structure-activity relationship
Stable Isotope Probing:Linking Functional Activity to Specific Members of Microbial Communities
期刊论文
OAI收割
Soil Science Society of America journal, 2007, 卷号: 71, 期号: 2, 页码: 611-619
KREUZER-MARTIN Helen W.
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2010/12/27
Soil Biology
Soil Science
Microbiology
Ecology
Molecular Biology
Biochemical Compound
Biological Activity
Molecular Methods
Isotopic Probe
Stable Isotopes
Soils
Lipids
Nucleic Acid
Fatty Acids
Substrate
Isotopes
Community Structure
Functional Group
Microbial Activity
Isotope Labelling
Investigation Method
Analysis Method
Microbial Community
Review
Three-dimensional quantitative structure-activity relationship of 4,5,6,7-tetrahydrothienopyridines analogues as glucose-6-phosphatase inhibitors
期刊论文
OAI收割
journal of molecular structure, 2006, 卷号: 782, 期号: 1, 页码: 49-54
作者:
Wang, C
;
Yang, L
;
Yang, SL
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2015/11/11
glucose-6-phosphatase
4
three-dimensional quantitative structure-activity relationship
partial least
comparative molecular field analysis
5
6
7-tetrahydrothienopyridines analogues
Quantitative structure-activity relationship for prediction of the toxicity of polybrominated diphenyl ether (PBDE) congeners
期刊论文
OAI收割
CHEMOSPHERE, 2006, 卷号: 64, 期号: 4, 页码: 515-524
作者:
Wang, Yawei
;
Zhao, Chunyan
;
Ma, Weiping
;
Liu, Hanxia
;
Wang, Thanh
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2015/10/15
polybrominated diphenyl ethers
quantitative structure activity relationships
prediction
principal component analysis