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The critical components for effective adaptive radiotherapy in patients with unresectable non-small-cell lung cancer: who, when and how 期刊论文 OAI收割
FUTURE ONCOLOGY, 2022
作者: Zhou, Suna; Meng, Yinnan; Sun, Xuefeng; Jin, Zhicheng; Feng, Wei

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ART how NSCLC when who

No pulsed radio emission during a bursting phase of a Galactic magnetar 期刊论文 OAI收割
Nature, 2020, 卷号: 587, 页码: 63-65
作者: HXMT

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Astrophysics - High Energy Astrophysical Phenomena Abstract: Fast radio bursts (FRBs) are millisecond-duration radio transients of unknown physical origin observed at extragalactic distances^1-3. It has long been speculated that magnetars are the engine powering repeating bursts from FRB sources^4-13, but no convincing evidence has been collected so far¹⁴. Recently, the Galactic magnetar SRG 1935+2154 entered an active phase by emitting intense soft íray bursts¹⁵. One FRB-like event with two peaks (FRB 200428) and a luminosity slightly lower than the faintest extragalactic FRBs was detected from the source, in association with a soft íray/hard-X-ray flare^18-21. Here we report an eight-hour targeted radio observational campaign comprising four sessions and assisted by multi-wavelength (optical and hard-X-ray) data. During the third session, 29 soft-íray repeater (SGR) bursts were detected in íray energies. Throughout the observing period, we detected no single dispersed pulsed emission coincident with the arrivals of SGR bursts, but unfortunately we were not observing when the FRB was detected. The non-detection places a fluence upper limit that is eight orders of magnitude lower than the fluence of FRB 200428. Our results suggest that FRB-SGR burst associations are rare. FRBs may be highly relativistic and geometrically beamed, or FRB-like events associated with SGR bursts may have narrow spectra and characteristic frequencies outside the observed band. It is also possible that the physical conditions required to achieve coherent radiation in SGR bursts are difficult to satisfy, and that only under extreme conditions could an FRB be associated with an SGR burst.

An underlying clock in the extreme flip-flop state transitions of the black hole transient Swift J1658.2-4242 期刊论文 OAI收割
Astronomy and Astrophysics, 2020, 卷号: 641, 页码: A101
作者: HXMT

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accretion accretion disks black hole physics X-rays: binaries time Astrophysics - High Energy Astrophysical Phenomena Abstract:
Aims: Flip-flops are top-hat-like X-ray flux variations, which have been observed in some transient accreting black hole binary systems, and feature simultaneous changes in the spectral hardness and the power density spectrum (PDS). They occur at a crucial time in the evolution of these systems, when the accretion disc emission starts to dominate over coronal emission. Flip-flops remain a poorly understood phenomenon, so we aim to thoroughly investigate them in a system featuring several such transitions.
Methods: Within the multitude of observations of Swift J1658.2-4242 during its outburst in early 2018, we detected 15 flip-flops, enabling a detailed analysis of their individual properties and the differences between them. We present observations by XMM-Newton, NuSTAR, Astrosat, Swift, Insight-HXMT, INTEGRAL, and ATCA. We analysed their light curves, searched for periodicities, computed their PDSs, and fitted their X-ray spectra, to investigate the source behaviour during flip-flop transitions and how the interval featuring flip-flops differs from the rest of the outburst.
Results: The flip-flops of Swift J1658.2-4242 are of an extreme variety, exhibiting flux differences of up to 77% within 100 s, which is much larger than what has been seen previously. We observed radical changes in the PDS simultaneous with the sharp flux variations, featuring transitions between the quasi-periodic oscillation types C and A, which have never been observed before. Changes in the PDS are delayed, but more rapid than changes in the light curve. Flip-flops occur in two intervals within the outburst, separated by about two weeks in which these phenomena were not seen. Transitions between the two flip-flop states occurred at random integer multiples of a fundamental period of 2.761 ks in the first interval and 2.61 ks in the second. Spectral analysis reveals the high and low flux flip-flop states to be very similar, but distinct from intervals lacking flip-flops. A change of the inner temperature of the accretion disc is responsible for most of the flux difference in the flip-flops. We also highlight the importance of correcting for the influence of the dust scattering halo on the X-ray spectra.

烟台牟平海洋牧场季节性低氧对大型底栖动物群落的生态效应 期刊论文 OAI收割
生物多样性, 2019, 卷号: 27, 期号: 2, 页码: 200-210
作者: 李宝泉

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低氧群落结构群落恢复敏感种机会种 hypoxia community structure community recovery sensitive species opportunistic species Hypoxia is a common phenomenon in the world's oceans, especially in the shallow waters of coastal zones. Rates of hypoxia are increasing due to global climatic changes and anthropogenic activities. Hypoxia can cause mass mortality of marine animals and can have severe negative impacts on marine ecosystems. To better understand the effects of hypoxia on macrobenthic communities, a survey was carried out in the Muping Marine Ranch (Yantai) during June, August and September of 2016. Results showed that seasonal hypoxia led to changes in benthic community structure, especially in terms of species composition and dominant species. The dominant species were Polychaeta Lumbrinereis latreilli, Sternaspis scutata and Mollusca Endopleura lubrica in summer. The opportunistic species Lumbrinereis latreilli increased, whereas, sensitive species such as Leptomya minuta, Glycera chirori, Upogebia major, Pontocrates altamarimus, Eriopisella sechellensis decreased during the hypoxic period of August. Hypoxia also reduced biodiversity indices. The effect of hypoxia on abundance and biomass were not significant, mainly because of the increase in the opportunistic Lumbrinereis latreilli, which counteracted the decline in abundance and biomass of other species. Individual physiological tolerance to hypoxia was different among species. Lumbrinereis latreilli showed higher tolerance to hypoxia in dissolved oxygen (DO) = 1.0 mg/L compared to other species. Some sensitive species, such as Leptomya minuta, Upogebia major, Pontocrates altamarimus and Eriopisella sechellensis showed lower tolerance when DO < 2.5 mg/L. When DO increased to 2.5 mg/L, the macrobenthic community start to recover gradually. The recovery extent and time needed were closely related to the degree of seasonal hypoxia.

碳氮稳定同位素比值在潮间带大型底栖动物组织间差异性研究 期刊论文 OAI收割
海洋学报, 2019, 卷号: 41, 期号: 4, 页码: 74-82
作者: 李宝泉

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潮间带大型底栖动物碳氮稳定同位素食源和营养级分析采样部位选取 intertidal zone macrobenthos carbon and nitrogen stable isotopes food sources and trophic levels study,sampling parts The technique of stable isotope analysis has been widely applied for the field of food web studies in recent years.However,few researches concerned about the impacts of different tissues used for analysis on the food web building.With the purpose of accuracy and comparability in the food web studies,the sampling tissues should be standardized.In this study,10macrobenthic species from the intertidal zone of the Yellow River Delta and Yantai were chosen as the target object to test the isotopic characteristic variations ofdelta~(13)C anddelta15 N at different body parts (whole bodies,muscles and gills).Our results show thatdelta~(13)C anddelta15 N values vary in different sampling tissues for most species,which indicates the different tissues used for analysis impact the food web building.To achieve a more accuracy and comparability result,suitable tissue should be primarily chosen for their food sources and trophic levels analysis.Namely,when the organism as predator,their muscles should first be chosen,for examples,adductor and foot muscles of mollusks,leg muscles of crabs and back muscles of fishes when the organism as prey, most of their tissues,except for indigestible part(for polychaetes,the digestive tract contents should be removed) should be chosen for analysis on food sources and trophic levels of the secondary consumer,for example,whole soft parts of mollusks,the mixture of muscles and gills of crabs.

食用蔬菜能吸收和积累微塑料 期刊论文 OAI收割
科学通报, 2019, 卷号: 64, 期号: 9, 页码: 928-934
作者: 李连祯; 周倩; 尹娜; 涂晨; 骆永明

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微塑料生菜聚苯乙烯微球吸收积累健康风险 microplastics lettuce polystyrene microbeads uptake accumulation human health risk Microplastic (MP, 100 nm-5 mm) may present an attributable risk to ecosystem and human health, and its pollution has become a global environmental concern. Despite a wealth of information on the accumulation of MPs in aquatic species, there is no information on the uptake and accumulation of MPs by higher plants. Terrestrial edible plants are directly exposed to MPs when agricultural soil was applied with organic manure, sewage sludge as fertilizer or plastic mulching. In this paper, the uptake of two sizes of polystyrene (PS) microbeads (0.2 and 1.0 mum) and then their distribution and migration in an edible plant lettuce were firstly investigated based on laboratory experiments. We used fluorescent markers to track PS microbeads in plant tissues and found fluorescence to be a sensitive and reliable detection method. Sections from untreated control lettuce showed no autofluorescence. When roots were treated with fluorescently labeled PS microbeads, the microbeads could be identified by its fluorescence. Our main study investigated the uptake of 0.2 mum beads, as few luminescence signals were observed in lettuce roots for 1.0 mum beads in our experiment. We observed that 0.2 mum fluorescent microbeads were extracellularly trapped in the root cap mucilage (which is a highly hydrated polysaccharide) and a dark green tip (which was typical of lettuce roots exposed to label PS beads) was usually visible to the naked eye. Confocal images revealed that the PS luminescence signals were mainly located in the vascular system and on the cell walls of the cortex tissue of the roots, indicated that the beads passed through the intercellular space via the apoplastic transport system. Once inside the central cylinder, the 0.2 mum PS beads were transferred from the roots to the stems and leaves via the vascular system following the transpiration stream. We also observed that the PS beads adhered to one another and self-assembled systematically into grape-like and (chain) string-like clusters in the intercellular space of the root and stem vascular tissue of lettuce plant. In contrast to the root and stem, PS beads were dispersed in the leaf tissue. Here, for the first time we provide evidence of the adherence, uptake, accumulation, and translocation of submicrometer MPs within an edible plant. Our findings highlight the previously underappreciated human exposure pathway to MPs through the consumption of contaminated crops and emphasize the need for new management strategies to control the release of MPs waste products into the terrestrial environment. Ultimately, the potential impacts of low range sized MPs on food safety of crop plants and human health need to be urgently considered.

Timing analysis of Swift J1658.2-4242's outburst in 2018 with Insight-HXMT, NICER and AstroSat 期刊论文 OAI收割
Journal of High Energy Astrophysics, 2019, 卷号: 24, 页码: 30-40
作者: HXMT

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Accretion accretion disks Black hole physics X-rays: binaries: Swift J1658.2-4242 Astrophysics - High Energy Astrophysical Phenomena Abstract: We present the observational results from a detailed timing analysis of the black hole candidate Swift J1658.2-4242 during its 2018 outburst with the observations of Hard X-ray Modulation Telescope (Insight-HXMT), Neutron Star Interior Composition Explorer (NICER) and AstroSat in 0.1-250 keV. The evolution of intensity, hardness and integrated fractional root mean square (rms) observed by Insight-HXMT and NICER are presented in this paper. Type-C quasi-periodic oscillations (QPOs) observed by NICER (0.8-3.5 Hz) and Insight-HXMT (1-1.6 Hz) are also reported in this work. The features of the QPOs are analyzed with an energy range of 0.5-50 keV. The relations between QPO frequency and other characteristics such as intensity, hardness and QPO rms are carefully studied. The timing and spectral properties indicate that Swift J1658.2-4242 is a black hole binary system. Besides, the rms spectra of the source calculated from the simultaneous observation of Insight-HXMT, NICER and AstroSat support the Lense-Thirring origin of the QPOs. The relation between QPO phase lag and the centroid frequency of Swift J1658.2-4242 reveals a near zero constant when < 4Hz and a soft phase lag at 6.68 Hz. This independence follows the same trend as the high inclination galactic black hole binaries such as MAXI J1659-152.

A New Set of Parameters of High-Mass X-ray Binaries Found with their Cyclotron Lines 期刊论文 OAI收割
arXiv e-prints, 2018
作者: Zhang, Chengmin; Taani, Ali; Chaty, Sylvain; Karino, Shigeyuki; Song, Liming

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Astrophysics - High Energy Astrophysical Phenomena Abstract: We have derived new physical quantities for several High-Mass X-ray Binaries (HMXBs) with supergiant (SG) companions through their cyclotron lines. The parameters are: the terminal velocity of the wind, the mass loss rate of the donor, the effective temperature and the magnetic fields. These parameters influence significantly the improvement of the model of accretion. In spite of the variety of their observational properties, the corresponding magnetic field is around B ~ 10^12 G. This result can be constrained by the effects on stellar evolution. In addition, we have performed a segmentation in the parameter space of donors intended for several SG-HMXB listed in our sample set. The parameter space can be categorized into five regimes depending on the possibility of disk formation associated with accretion from the stellar wind. This can give a quantitative clarification of the observed variability and the properties of these objects. We show that, when these systems come into the direct accretion region, systems with corresponding parameters can emit X-rays.

Rapid Micro-Patterning of a Conductive PANI/MWNTs-Polymer Composite Using an Optically-induced Electrokinetics Chip 会议论文 OAI收割
IEEE Nanotechnology Materials and Devices Conference (IEEE NMDC), Honolulu, HI, OCT 16-19, 2012
作者: Liu N(刘娜); Liang WF(梁文峰); Mai, John D.; Dong ZL(董再励); Li WJ(李文荣)

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A flexible, dynamically programmable and low-cost method applicable to micro-patterning of a conductive polymer/carbon nanotube composite solution is significant due to the potential applications in many areas. This paper demonstrates a new micro-patterning method for fabricating electrodes from a conductive polyaniline (PANI)/MWNT composite using an optically-induced electrokinetics (OEK) chip. This method quickly patterns flexible polymeric electrodes with different geometries when a square waveform signal with amplitudes from 16-20 Volts and frequencies from 20-30 kHz are applied. The geometric dimensions of the electrodes can be varied dynamically by controlling the size and exposure time of the light pattern. The surface morphology of electrodes patterned by this method is scanned by an atomic force microscope (AFM) and a scanning electron microscope (SEM) which show that the electrodes are uniform and continuous. Furthermore, the geometric dimensions and resistances of the electrodes are measured and analyzed. Experimental results reveal that the relationship between the resistance and geometries of the electrodes obey Ohm's law and the resistivity of the electrodes is about 0.03 Omega.m.

Tribological properties of Mos2 thin coatings under liquid lubricating (EI CONFERENCE) 会议论文 OAI收割
2nd International Conference on Innovation Manufacturing and Engineering Management, IMEM 2012, December 14, 2012 - December 16, 2012, Chongqing, China
Bai Y.; Cao P.

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The objective of this study is to investigate the effect of solid and liquid lubrication on friction and wear performance of selected solid lubricating coatings comparative experiments have been carried out on magnetron sputtered MoS2 coatings against Si3N4 ball using a ball-on-disk tribo-tester under the conditions of room temperature and different lubrication. Surface morphology of coatings were investigated by atom force microscope (AFM) and friction coefficient (COF) and wear rate of solid films were also be analyzed. It was shown that the friction is greatly reduced when the solid film is lubricated with oil and grease simultaneously in comparison with single-lubricant lubrication at the start-up or under boundary lubrication conditions. Liquid lubrication causes a dramatic decrease of the wear-ability of the MoS2 coatings. The effect of oil lubrication to the deterioration of wear resistance of MoS2 film was even worse than lubrication grease. (2013) Trans Tech Publications Switzerland.