机构

• 生物物理研究所 [2]
• 上海药物研究所 [1]

采集方式

• OAI收割 [3]

内容类型

• 期刊论文 [3]

发表日期

• 2018 [1]
• 2009 [1]
• 2008 [1]

学科主题

• Biochemist... [1]
• Pharmacolo... [1]

筛选

浏览/检索结果: 共3条，第1-3条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis and structure-activity relationship evaluation of novel LpxC inhibitors as Gram-negative antibacterial agents 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 2, 页码: 94-102 作者:  Ding, Shi;  Dai, Rui-Yang;  Wang, Wen-Ke;  Cao, Qiao;  Lan, Le-Fu   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 Gram-negative bacteria infection  LpxC inhibitor  Structure-activity relationship  Zinc binding group  Liver microsomal stability   Characterization of alpha-nitromethyl ketone as a new zinc-binding group based on structural analysis of its complex with carboxypeptidase A 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 卷号: 19, 期号: 17, 页码: 5009-5011 Wang, ShouFeng; Tian, Guan Rong; Zhang, WenZheng; Jin, JingYi 收藏  |  浏览/下载：21/0  |  提交时间：2013/12/25 Zinc-binding group  Crystal structure  Transition-state analog   Nitro as a novel zinc-binding group in the inhibition of carboxypeptidase A 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2008, 卷号: 16, 期号: 7, 页码: 3596-3601 Wang, SiHong; Wang, ShouFeng; Xuan, Wei; Zeng, Zonghao; 曾宗浩; Jin, JingYi; Ma, Jie; Tian, Guan Rong 收藏  |  浏览/下载：26/0  |  提交时间：2013/12/25 carboxypeptidase A  inhibition  nitro  zinc-binding group  X-ray crystallography  transition-state analog inhibitor