中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [22]
西北高原生物研究所 [9]
中国科学院大学 [2]
深圳先进技术研究院 [1]
成都生物研究所 [1]
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期刊论文 [40]
学位论文 [1]
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2022 [1]
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2020 [3]
2019 [3]
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Cell Biolo... [1]
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Rutaecarpine Promotes Adipose Thermogenesis and Protects against HFD-Induced Obesity via AMPK/PGC-1 alpha Pathway
期刊论文
OAI收割
PHARMACEUTICALS, 2022, 卷号: 15, 期号: 4, 页码: 18
作者:
Chen, Dandan
;
Duan, Yanan
;
Yu, Shuxiang
;
Zhang, Xinwen
;
Li, Ni
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
obesity
rutaecarpine
adipocytes
thermogenesis
peroxisome-proliferator-activated receptor gamma co-activator-1 alpha
AMP-activated protein kinase
browning
Optimization and Development of a Scalable Palladium-Catalyzed C-H Activation Process for the Geometry-Selective Preparation of Kilograms of YLF466D, a Potent AMP-Activated Protein Kinase Activator
期刊论文
OAI收割
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2021, 卷号: 25, 期号: 10, 页码: 2260-2269
作者:
Yin, Jianpeng
;
Zhan, Desheng
;
Ma, Hui
;
Liu, Huanan
;
Yu, Lifang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/12/16
YLF466D
AMPK activator
glucose metabolism
lipid metabolism
MIRI
domino reaction
C-H activation
Effects of dibutyl phthalate on lipid metabolism in liver and hepatocytes based on PPAR alpha/SREBP-1c/FAS/GPAT/AMPK signal pathway
期刊论文
OAI收割
FOOD AND CHEMICAL TOXICOLOGY, 2021, 卷号: 149
作者:
Zhang, Wang
;
Li, Jing-Ya
;
Wei, Xiao-Chen
;
Wang, Qian
;
Yang, Ji-Yang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/04/26
DBP
PPAR alpha
AMPK
Lipid metabolism
Liver function
DW14006 as a direct AMPK alpha 1 activator improves pathology of AD model mice by regulating microglial phagocytosis and neuroinflammation
期刊论文
OAI收割
BRAIN BEHAVIOR AND IMMUNITY, 2020, 卷号: 90, 页码: 55-69
作者:
Lv, Jianlu
;
Wang, Wei
;
Zhu, Xialin
;
Xu, Xiaoju
;
Yan, Qiuying
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/21
Alzheimer'sdisease
Microglia
AMPK alpha 1
DW14006
Phagocytosis
Neuro-inflammation
DW14006 as a Direct AMPK alpha Activator Ameliorates Diabetic Peripheral Neuropathy in Mice
期刊论文
OAI收割
DIABETES, 2020, 卷号: 69, 期号: 9, 页码: 1974-1988
作者:
Xu, Xu
;
Wang, Wei
;
Wang, Zhengyu
;
Lv, Jianlu
;
Xu, Xiaoju
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/24
AMPK activator C24 inhibits hepatic lipogenesis and ameliorates dyslipidemia in HFHC diet-induced animal models
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Sun, Shui-mei
;
Xie, Zhi-fu
;
Zhang, Yang-ming
;
Zhang, Xin-wen
;
Zhou, Chen-dong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/12/24
adenosine 5 '-monophosphate-activated protein kinase
AMPK activator
C24
liver
triglycerides
cholesterol
VLDL
hypolipidemic drug
metabolic syndrome
Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
期刊论文
OAI收割
CELL METABOLISM, 2019, 卷号: 30, 期号: 3, 页码: 508-+
作者:
Li, Mengqi
;
Zhang, Chen-Song
;
Zong, Yue
;
Feng, Jin-Wei
;
Ma, Teng
  |  
收藏
  |  
浏览/下载:152/0
  |  
提交时间:2019/12/02
Lipid-modified cell-penetrating peptide-based self-assembly micelles for co-delivery of narciclasine and siULK1 in hepatocellular carcinoma therapy
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2019, 卷号: 74, 页码: 414-429
作者:
Wang, Xiaoyun
;
Wu, Fengbo
;
Li, Guoyou
;
Zhang, Nan
;
Song, Xiangrong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/24
Hepatocellular carcinoma
Narciclasine
Cell penetrating peptide
Codelivery
Autophagy
ULK1
Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study
期刊论文
OAI收割
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 79, 页码: 165-176
作者:
Li, Yingying
;
Peng, Jiale
;
Li, Penghua
;
Du, Haibo
;
Li, Yaping
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2019/07/29
Pharmacophore modeling
Molecular docking
Quantitative structure activity relationship (QSAR)
Molecular dynamics
AMPK
Activator
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice