中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共159条,第1-10条 帮助

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An MnO2-ZIF-67 immobilized acetylcholinesterase method for acetylcholinesterase activity assay and inhibitor screening from Inula macrophylla based on capillary electrophoresis 期刊论文  OAI收割
Talanta, 2023, 期号: 253, 页码: 124025
作者:  
Jia Liu;  Rui Ma;  Wei Ha;  Hai-Xia Zhang;  Shi YP(师彦平)
  |  收藏  |  浏览/下载:44/0  |  提交时间:2022/11/30
Ruptured organosilica nanocapsules immobilized acetylcholinesterase coupled with MnO2 nanozyme for screening inhibitor from Inula macrophylla 期刊论文  OAI收割
Nanoscale, 2023, 期号: 15, 页码: 17464-17472
作者:  
Jia Liu;  Wei Ha;  Eshbakova Komila Alibekovna;  Rui Ma;  Shi YP(师彦平)
  |  收藏  |  浏览/下载:2/0  |  提交时间:2023/11/13
An MnO2-ZIF-67 immobilized acetylcholinesterase method for acetylcholinesterase activity assay and inhibitor screening from Inula macrophylla based on capillary electrophoresis 期刊论文  OAI收割
Talanta, 2022, 期号: 253, 页码: 124025
作者:  
Jia Liu;  Rui Ma;  Wei Ha;  Hai-Xia Zhang;  Shi YP(师彦平)
  |  收藏  |  浏览/下载:14/0  |  提交时间:2022/11/30
Novel inhibitors of AChE and A0 aggregation with neuroprotective properties as lead compounds for the treatment of Alzheimer's disease 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235, 页码: 22
作者:  
Liu, Yulin;  Uras, Giuseppe;  Onuwaje, Itse;  Li, Wenlong;  Yao, Hong
  |  收藏  |  浏览/下载:27/0  |  提交时间:2022/08/16
Design, synthesis, in vitro evaluation of a new pyrrolo[1,2-a]thiazolo[5,4-d]pyrimidinone derivatives as cholinesterase inhibitors against Alzheimer's disease 期刊论文  OAI收割
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2022, 页码: 16
作者:  
Zeng, Yan;  Nie, Lifei;  Liu, Liu;  Niu, Chao;  Li, Yi
  |  收藏  |  浏览/下载:26/0  |  提交时间:2022/06/15
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:  
Li, Xiaokang;  Li, Jinwen;  Huang, Yunyuan;  Gong, Qi;  Fu, Yan
  |  收藏  |  浏览/下载:31/0  |  提交时间:2022/06/15
Desorption electrospray ionization (DESI) source coupling ion mobility mass spectrometry for imaging fluoropezil (DC20) distribution in rat brain 期刊论文  OAI收割
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2021, 页码: 13
作者:  
Guo, Runcong;  Zhou, Lei;  Chen, Xiaoyan
  |  收藏  |  浏览/下载:17/0  |  提交时间:2021/11/04
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:  
Zhou, Yu;  Fu, Yan;  Yin, Wanchao;  Li, Jian;  Wang, Wei
  |  收藏  |  浏览/下载:22/0  |  提交时间:2021/05/24
Discovery and Biological Evaluation of New Selective Acetylcholinesterase Inhibitors with Anti-A beta Aggregation Activity through Molecular Docking-Based Virtual Screening 期刊论文  OAI收割
CHEMICAL & PHARMACEUTICAL BULLETIN, 2020, 卷号: 68, 期号: 2, 页码: 161-166
作者:  
Liu, Guangpu;  Jiao, Yang;  Lin, Yongqiang;  Hao, Haifang;  Dou, Yanli
  |  收藏  |  浏览/下载:22/0  |  提交时间:2020/07/01
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  
Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li
  |  收藏  |  浏览/下载:34/0  |  提交时间:2020/03/18