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上海药物研究所 [12]
大连化学物理研究所 [6]
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Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634
Authors:
Xiong, Jiacheng
;
Cui, Rongrong
;
Li, Zhaojun
;
Zhang, Wei
;
Zhang, Runze
  |  
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  |  
View/Download:9/0
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Submit date:2024/05/07
Drug metabolism
Aldehyde oxidase
Transfer learning
Graph neural network
Kinase inhibitor
Revisiting Aldehyde Oxidase Mediated Metabolism in Drug-like Molecules: An Improved Computational Model
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 12, 页码: 6523-6537
Authors:
Zhao, Jihui
;
Cui, Rongrong
;
Wang, Lihao
;
Chen, Yingjia
;
Fu, Zunyun
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View/Download:22/0
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Submit date:2020/12/24
Nimesulide increases the aldehyde oxidase activity of humans and rats
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
Authors:
Zhou, Lei
;
Pang, Xiao-yan
;
Hou, Xiang-yu
;
Liu, Lu
;
Guo, Zi-tao
  |  
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View/Download:25/0
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Submit date:2020/07/01
nimesulide
aldehyde oxidase
induction
methotrexate
hepatocytes
pharmacokinetics
drug interaction
Grapevine U-Box E3 Ubiquitin Ligase VlPUB38 Negatively Regulates Fruit Ripening by Facilitating Abscisic-Aldehyde Oxidase Degradation
期刊论文
OAI收割
PLANT AND CELL PHYSIOLOGY, 2020, 卷号: 61, 期号: 12, 页码: 2043-2054
Authors:
Yu, Yihe
;
Meng, Xiangxuan
;
Guo, Dalong
;
Yang, Shengdi
;
Zhang, Guohai
  |  
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  |  
View/Download:23/0
  |  
Submit date:2022/01/06
ABA
Degradation
E3 ubiquitin ligase
Fruit ripening
Ubiquitination
Grapevine U-Box E3 Ubiquitin Ligase VlPUB38 Negatively Regulates Fruit Ripening by Facilitating Abscisic-Aldehyde Oxidase Degradation
期刊论文
OAI收割
PLANT AND CELL PHYSIOLOGY, 2020, 卷号: 61, 期号: 12, 页码: 2043-2054
Authors:
Yu, Yihe
;
Meng, Xiangxuan
;
Guo, Dalong
;
Yang, Shengdi
;
Zhang, Guohai
  |  
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  |  
View/Download:16/0
  |  
Submit date:2022/03/01
ABA
Degradation
E3 ubiquitin ligase
Fruit ripening
Ubiquitination
The metabolism distribution and effect of imidacloprid in chinese lizards (Eremias argus) following oral exposure
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2018, 卷号: 165, 页码: 476-483
Authors:
Li, Wei
;
Wang, Yinghuan
;
Han, Yongtao
;
Xu, Peng
;
Guo, Baoyuan
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View/Download:203/0
  |  
Submit date:2019/06/21
Eremias argus
Imidacloprid
Metabolism
Distribution
Chemoenzymatic Approach for the Proteomics Analysis of Mucin-Type Core-1 O-Glycosylation in Human Serum
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2018, 卷号: 90, 期号: 21, 页码: 12714-12722
Authors:
You, Xin
;
Yao, Yating
;
Mao, Jiawei
;
Qin, Hongqiang
;
Liang, Xinmiao
  |  
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  |  
View/Download:59/0
  |  
Submit date:2019/06/20
Chemoenzymatic approach for the proteomics analysis of mucin-type core-1 o-glycosylation in human serum
期刊论文
iSwitch采集
Analytical chemistry, 2018, 卷号: 90, 期号: 21, 页码: 12714-12722
Authors:
You, Xin
;
Yao, Yating
;
Mao, Jiawei
;
Qin, Hongqiang
;
Liang, Xinmiao
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View/Download:69/0
  |  
Submit date:2019/05/08
The metabolism distribution and effect of dinotefuran in Chinese lizards (Eremias argus)
期刊论文
OAI收割
CHEMOSPHERE, 2018, 卷号: 211, 页码: 591-599
Authors:
Xu, Peng
;
Wang, Yinghuan
;
Han, Yongtao
;
Xie, Yun
;
Li, Wei
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View/Download:34/0
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Submit date:2019/06/21
Eremias argus
Dinotefuran
Metabolism
Distribution
Evaluation of Deuterium-Labeled JNJ38877605: Pharmacokinetic, Metabolic, and in Vivo Antitumor Profiles
期刊论文
OAI收割
CHEMICAL RESEARCH IN TOXICOLOGY, 2018, 卷号: 31, 期号: 11, 页码: 1213-1218
Authors:
Zhan, Zhengsheng
;
Peng, Xia
;
Sun, Yiming
;
Ai, Jing
;
Duan, Wenhu
  |  
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View/Download:26/0
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Submit date:2019/01/08