中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [44]
西北高原生物研究所 [21]
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期刊论文 [114]
学位论文 [11]
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Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity
Optimization of potent, selective and orally bioavailable biphenyl scaffold as FABP4 inhibitors for anti-inflammation
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 253, 页码: 16
作者:
He, Yulong
;
Li, Shunyi
;
Zhu, Yueyue
;
Wang, Yujie
;
Chen, Yuqi
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2023/10/17
Structure-activity relationship
FABP4 inhibitor
Biphenyl scaffold
Selectivity
Oral bioavailability
Anti-inflammation
14-Deoxygarcinol improves insulin sensitivity in high-fat diet-induced obese mice via mitigating NF-κB/Sirtuin 2-NLRP3-mediated adipose tissue remodeling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 2, 页码: 434
作者:
Chen Jiali
;
Feng Zheling
;
Zhou Fei
;
Lou Ruohan
;
Peng Cheng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/05/22
14-deoxygarcinol
adipose tissue inflammation
insulin resistance
interleukin-1β
NLRP3 inflammasome
Sirtuin 2
Limosilactobacillus reuteri and caffeoylquinic acid synergistically promote adipose browning and ameliorate obesity-associated disorders
期刊论文
OAI收割
MICROBIOME, 2022, 卷号: 10, 期号: 1, 页码: 22
作者:
Liu, Yameng
;
Zhong, Xianchun
;
Lin, Suqin
;
Xu, Hualing
;
Liang, Xinyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Obesity
Prebiotic
Probiotics
Short-chain fatty acids
Propionate
Thermogenesis
Browning
Bioactivity-based molecular networking-guided identification of guttiferone J from Garcinia cambogia as an anti-obesity candidate
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2022, 页码: 20
作者:
Feng, Zheling
;
Chen, Jiali
;
Chen, Cheng
;
Feng, Lu
;
Wang, Rui
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
anti-obesity
bioactivity-based molecular networking
Garcinia cambogia
guttiferone J
sirtuin 3
white adipose tissue browning
Aloe Vera-Fermented Beverage Ameliorates Obesity and Gut Dysbiosis in High-Fat-Diet Mice
期刊论文
OAI收割
FOODS, 2022, 卷号: 11, 期号: 22, 页码: 15
作者:
Fu, Shijie
;
Dang, Yanting
;
Xu, Huilin
;
Li, Aimin
;
Zhou, Xiaoman
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/02/24
obesity
fermented beverages
Aloe vera
gut microbiota
The Complex of Phycobiliproteins, Fucoxanthin, and Krill Oil Ameliorates Obesity through Modulation of Lipid Metabolism and Antioxidants in Obese Rats
期刊论文
OAI收割
NUTRIENTS, 2022, 卷号: 14, 期号: 22, 页码: 12
作者:
Qiang, Xi
;
Guo, Chuanlong
;
Gu, Wenhui
;
Song, Yuling
;
Zhang, Yuhong
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/01/04
obesity
lipid metabolism
phycobiliproteins
fucoxanthin
krill oil
Efficient Detection of Pre-Proinsulin by Double Antibody Sandwich ELISA
期刊论文
OAI收割
APPLIED SCIENCES-BASEL, 2022, 卷号: 12
作者:
Zhu, Zhu
;
Wang, Han
;
Wang, Li
;
Wei, Zhou
;
Zheng, Zhiming
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
recombinant human insulin
pre-proinsulin
monoclonal antibody
sandwich ELISA
Development and structure–activity relationships of tanshinones as selective 11β-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural Products and Bioprospecting, 2022, 卷号: 12, 期号: 1
作者:
Deng,Xu
;
Huang,Su-Ling
;
Ren,Jian
;
Pan,Zheng-Hong
;
Shen,Yu
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/11/11
Metabolic syndrome
Tanshinones
Selective 11β-HSD1 inhibitors
Structure–activity relationships
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones