中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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A novel phthalazinone derivative as a capsid assembly modulator inhibits hepatitis B virus expression
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2024, 卷号: 221, 页码: 14
作者:
Yang, Li
;
Gong, Ying
;
Liu, Feifei
;
Chen, Wuhong
;
Wang, Xinran
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/02/19
Hepatitis B virus
Capsid assembly
Phthalazinone derivatives
Apoptosis
Safety, tolerability and pharmacokinetics of forsythin in healthy subjects: a double-blinded, placebo-controlled single-dose and multiple-dose escalation and food effect study
期刊论文
OAI收割
ANNALS OF MEDICINE, 2023, 卷号: 55, 期号: 2, 页码: 9
作者:
Li, Cuiyun
;
Wu, Min
;
Zhang, Hong
;
Zhu, Xiaoxue
;
Fu, Li
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
Forsythin
pharmacokinetics
safety
tolerability
food effect
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Repurposing of Rutan showed effective treatment for COVID-19 disease
期刊论文
OAI收割
FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13
作者:
Salikhov, Shavkat I.
;
Abdurakhmonov, Ibrokhim Y.
;
Oshchepkova, Yuliya I.
;
Ziyavitdinov, Jamolitdin F.
;
Berdiev, Nodir Sh.
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/01/26
COVID-19
SARS-CoV-2
3CLpro
RdRp
Rhus coriaria
Rutan
clinical trial
Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11
作者:
Ye, Yaqing
;
Xue, Mingzhen
;
Tian, Xiaoting
;
Gao, Hongwei
;
Hu, Pei
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Anemoside B4
Pulsatilla chinensis
metabolite identification
Pharmacokinetics
Rectal suppository
Liang-Ge-San inhibits dengue virus serotype 2 infection by reducing caveolin1-induced cytoplasmic heat shock protein 70 translocation into the plasma membrane
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 119, 页码: 14
作者:
Chen, Xi
;
Yang, Jia-bin
;
Cao, Hui-hui
;
Fang, Xiao-chuan
;
Liu, Shan-hong
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/10/17
Liang-Ge-San
Dengue virus serotype 2
Heat shock protein 70
Caveolin1
Envelope protein
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:
Zhang, Yumin
;
Sun, Yuan
;
Xie, Yuanchao
;
Shang, Weijuan
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Efficient Large-Scale Process for Tecovirimat via Reactive Distillation for the Preparation of Cycloheptatriene
期刊论文
OAI收割
ORGANIC PROCESS RESEARCH & DEVELOPMENT, 2023, 页码: 8
作者:
Bonku, Emmanuel Mintah
;
Qin, Hongjian
;
Odilov, Abdullajon
;
Yang, Feipu
;
Xing, Xinglong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
tecovirimat
monkeypox
cycloheptatriene
antiviral drug
reactive distillation
Viruses in deep-sea cold seep sediments harbor diverse survival mechanisms and remain genetically conserved within species
期刊论文
OAI收割
ISME JOURNAL, 2023, 页码: 11
作者:
Peng, Yongyi
;
Lu, Zijian
;
Pan, Donald
;
Shi, Ling-Dong
;
Zhao, Zhao
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/07
Ocellatuspyrones A-G, new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
期刊论文
OAI收割
MARINE LIFE SCIENCE & TECHNOLOGY, 2023, 页码: 14
作者:
Li, Song-Wei
;
Yu, Dan-Dan
;
Su, Ming-Zhi
;
Yao, Li-Gong
;
Wang, Hong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Placobranchus ocellatus
gamma-pyrone polypropionate
Photosynthetic mollusk
Antibacterial activity
Stereochemistry