中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [91]
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A Near-infrared Fluorescence and Positron Emission Tomography Bimodal Probe for
I
n Vivo
I
maging of Amyloid-β Species
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2024, 卷号: 15, 期号: 3, 页码: 472-478
作者:
Fang, Daqing
;
Pan, Donghui
;
Wen, Xidan
;
Zhang, Junya
;
Yang, Min
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/13
A beta species
Alzheimer's disease
NIR fluorescence imaging
PET imaging
bimodalprobe
APP/PS1
Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Design, synthesis, and biological evaluation of novel spirocyclic compounds as potential anti-glioblastoma agents
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 22
作者:
Zhu, Heping
;
Song, Xiaomin
;
Pan, Yihui
;
Li, Ming
;
Chen, Liang
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Glioblastoma
Spirocyclic compounds
Drug design
Antiproliferation
Nanobiotechnology-based treatment strategies for malignant relapsed glioma
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 358, 页码: 681-705
作者:
Qiu, Qiujun
;
Ding, Xinyi
;
Chen, Jixiang
;
Chen, Sunhui
;
Wang, Jianxin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Recurrent glioma
Nanobiotechnology
Drug delivery system
Glioma microenvironment
Anti-glioma immune response
Blood tau-PT217 contributes to the anesthesia/surgery-induced delirium-like behavior in aged mice
期刊论文
OAI收割
ALZHEIMERS & DEMENTIA, 2023, 页码: 17
作者:
Lu, Jing
;
Liang, Feng
;
Bai, Ping
;
Liu, Chenghao
;
Xu, Miao
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/11/17
anesthesia
delirium
phosphorylated tau at threonine 217
surgery
tau
tau phosphorylation
Deep Penetrating and Sensitive Targeted Magnetic Particle Imaging and Photothermal Therapy of Early-Stage Glioblastoma Based on a Biomimetic Nanoplatform
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 11
作者:
Huang, Xiazi
;
Hui, Hui
;
Shang, Wenting
;
Gao, Pengli
;
Zhou, Yingying
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/11/17
biomimetic nanoplatform
brain-blood-barrier breaking
cancer diagnosis
glioblastoma multiforme
magnetic particle imaging
Nucleic acid drug vectors for diagnosis and treatment of brain diseases
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 53
作者:
Lu, Zhi-Guo
;
Shen, Jie
;
Yang, Jun
;
Wang, Jing-Wen
;
Zhao, Rui-Chen
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/05/19
Photostable Small-Molecule NIR-II Fluorescent Scaffolds that Cross the Blood-Brain Barrier for Noninvasive Brain Imaging
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2022, 卷号: 144, 期号: 51, 页码: 23668-23676
作者:
Wang, Shichao
;
Shi, Hui
;
Wang, Lushun
;
Loredo, Axel
;
Bachilo, Sergei M.
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
Design of an activatable NIR-II nanoprobe for the in vivo elucidation of Alzheimer's disease-related variations in methylglyoxal concentrations
期刊论文
OAI收割
CHEMICAL SCIENCE, 2022, 卷号: 13, 期号: 42, 页码: 12511-12518
作者:
Lai, Yi
;
Dang, Yijing
;
Sun, Qian
;
Pan, Jiaxing
;
Yu, Haijun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/13
Absorption, distribution, metabolism, and excretion of [C-14]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2022, 页码: 12
作者:
Li, Xin-mei
;
Zheng, Yuan-dong
;
Zhang, Yi-fan
;
Huan, Xia-juan
;
Yang, Chen
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/12/13
[C-14]Mefuparib
Mefuparib (CVL218)
Blood-brain barrier
Mass balance
Tissue distribution
GastroPlus simulation