机构

• 上海药物研究所 [8]
• 昆明植物研究所 [3]
• 近代物理研究所 [3]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [12]
• 会议论文 [2]

发表日期

• 2022 [1]
• 2021 [1]
• 2020 [1]
• 2019 [2]
• 2018 [1]
• 2015 [2]
• 更多

学科主题

• Oncology [2]
• Cell Biolo... [1]

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration   Comparable radiation sensitivity in p53 wild-type and p53 deficient tumor cells associated with different cell death modalities 期刊论文  OAI收割 CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 8 作者:  Li, Ping;  Liu, Xiongxiong;  Zhao, Ting   |  收藏  |  浏览/下载：39/0  |  提交时间：2021/12/09 Radiosensitization of NSCLC cells to X-rays and carbon ions by the CHK1/CHK2 inhibitor AZD7762, Honokiol and Tunicamycin 期刊论文  OAI收割 RADIATION AND ENVIRONMENTAL BIOPHYSICS, 2020, 页码: 10 作者:  Liu, Bingtao;  Chen, Weiqiang;  Li, Hongbin;  Li, Feifei;  Jin, Xiaodong   |  收藏  |  浏览/下载：9/0  |  提交时间：2021/12/15 Radiosensitivity  X-rays  Carbon ions  AZD7762  Honokiol  Tunicamycin   Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino) pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 173, 页码: 44-62 作者:     |  收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01 CHK1 kinase inhibitor  Selectivity  Monotherapy  Hematologic malignancies   Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文  OAI收割 TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83 作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan   |  收藏  |  浏览/下载：75/0  |  提交时间：2019/03/18 Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma   Acetyl-macrocalin B, an ent-kaurane diterpenoid, initiates apoptosis through the ROS-p38-caspase 9-dependent pathway and induces G2/M phase arrest via the Chk1/2-Cdc25C-Cdc2/cyclin B axis in non-small cell lung cancer 期刊论文  OAI收割 CANCER BIOLOGY & THERAPY, 2018, 卷号: 19, 期号: 7, 页码: 609-621 作者:  Wang, Jing-Nan;  Zhang, Zhi-Rong;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang   |  收藏  |  浏览/下载：108/0  |  提交时间：2018/07/16 Acetyl-macrocalin B  reactive oxygen species  p38 MAPK  apoptosis  Chk1  Chk2  G2  M phase arrest  NSCLC   Radiation-induced hyperproliferation of intestinal crypts results in elevated genome instability with inactive p53-related genomic surveillance 期刊论文  OAI收割 LIFE SCIENCES, 2015, 卷号: 143, 页码: 80-88 作者:  Zhou, Xin;  Ma, Xiaofei;  Wang, Zhenhua;  Sun, Chao;  Wang, Yupei   |  收藏  |  浏览/下载：25/0  |  提交时间：2018/05/31 NHEJ  Hyperproliferation  Intestinal crypt   A new arylbenzofuran derivative functions as an anti-tumour agent by inducing DNA damage and inhibiting PARP activity 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2015, 卷号: 5 作者:  Chen, Hongbo;  Zeng, Xiaobin;  Gao, Chunmei;  Ming, Pinghong;  Zhang, Jianping   |  收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells 期刊论文  OAI收割 ONCOTARGET, 2014, 卷号: 5, 期号: 3, 页码: 841-852 作者:  Zhang, Jingjie;  Gao, Guangxun;  Chen, Liang;  Li, Jingxia;  Deng, Xu 收藏  |  浏览/下载：36/0  |  提交时间：2014/05/16 Cheliensisin A  Apoptosis  colon cancer  p53  chemotherapeutic agent   Naphthalimides Induce G(2) Arrest Through the ATM-Activated Chk2-Executed Pathway in HCT116 Cells 期刊论文  OAI收割 NEOPLASIA, 2009, 卷号: 11, 期号: 11, 页码: 1226-1234 作者:  Zhu, Hong;  Miao, Ze-Hong;  Huang, Min;  Feng, Jian-Ming;  Zhang, Zhi-Xiang   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08