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浏览/检索结果: 共340条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Structure-Guided Design, Synthesis, and Antivirulence Assessment of Covalent Staphylococcus aureus Sortase A Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1127-1146 作者:  Yue, Chuan;  Yuan, Ziqi;  Xu, Guobin;  Guan, Xiang-Na;  Wei, Bingyan   |  收藏  |  浏览/下载：4/0  |  提交时间：2024/02/27 ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292 作者:  Jiang, Lulu;  Liu, Sixiu;  Jia, Xinglong;  Gong, Qinting;  Wen, Xin   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/16 Discovery of a highly potent NPAS3 heterodimer inhibitor by covalently modifying ARNT 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 10 作者:  Li, Peizhuo;  Tian, Yucheng;  Shang, Qinghong;  Tang, Cailing;  Hou, Zeng   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 NPAS3  Covalent inhibitor  Protein -protein interaction  5-nitrothiazole warhead   Orthogonally Engineered Albumin with Attenuated Macrophage Phagocytosis for the Targeted Visualization and Phototherapy of Liver Cancer 期刊论文  OAI收割 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 31, 页码: 17377-17388 作者:  Dou, Wei-Tao;  Qiu, Peng;  Shi, Yuanyuan;  Zhu, Ling;  Guo, Chen   |  收藏  |  浏览/下载：124/0  |  提交时间：2023/10/17 Structure-Based Design of Potent Peptidomimetic Inhibitors Covalently Targeting SARS-CoV-2 Papain-like Protease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 10, 页码: 15 作者:  Wang, Qian;  Chen, Guofeng;  He, Jian;  Li, Jiameng;  Xiong, Muya   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/10/17 SARS-CoV-2  papain-like protease  covalent inhibitor  co-crystal structure  in vitro assay   Unraveling the catalytic mechanism of SARS-CoV-2 papain-like protease with allosteric modulation of C270 mutation using multiscale computational approaches 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 18, 页码: 4681-4696 作者:  Shao, Qiang;  Xiong, Muya;  Li, Jiameng;  Hu, Hangchen;  Su, Haixia   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割 European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129 作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/26 Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Zhu, Mengwei;  Fu, Tiantian;  You, Mengyuan;  Cao, Junyuan;  Yang, Hanxi   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 COVID-19  SARS-CoV-2  3CL protease  Nirmatrelvir  Peptidomimetic inhibitors   Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors 期刊论文  OAI收割 NATURE CHEMISTRY, 2023, 页码: 18 作者:  Guo, An-Di;  Yan, Ke-Nian;  Hu, Hao;  Zhai, Linhui;  Hu, Teng-Fei   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 Celastrol suppresses colorectal cancer via covalent targeting peroxiredoxin 1 期刊论文  OAI收割 Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 3, 页码: 1159-1174 作者:  Xu, Heng;  Zhao, Hongfang;  Ding, Chunyong;  Jiang, Defang;  Zhao, Zijie   |  收藏  |  浏览/下载：10/0  |  提交时间：2024/03/27