机构

• 上海药物研究所 [4]
• 南海海洋研究所 [2]
• 水生生物研究所 [1]
• 昆明植物研究所 [1]
• 海洋研究所 [1]
• 武汉植物园 [1]
• 更多

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [10]
• 学位论文 [1]

发表日期

• 2023 [2]
• 2022 [1]
• 2021 [2]
• 2020 [3]
• 2019 [1]
• 2017 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16 作者:  Chen, Yun;  Ning, Yi;  Chen, Zhiwei;  Xue, Yaping;  Wu, Qingyun   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Apoptosis  Diffuse large B-Cell lymphoma  Interleukin-1 receptor associated kinase 4  Structure-based drug design  2  3-Dihydrobenzofuran   E3 ligase ligand optimization of Clinical PROTACs 期刊论文  OAI收割 FRONTIERS IN CHEMISTRY, 2023, 卷号: 11, 页码: 15 作者:  Jiang, Hanrui;  Xiong, Huan;  Gu, Shuang-Xi;  Wang, Mingliang   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10 PROTACs  E3 ubiquitin ligase ligand  structure optimization  clinical trials  CRBN   Environmental concentrations of 2, 4-DTBP cause immunotoxicity in zebrafish (Danio rerio) and may elicit ecological risk to wildlife 期刊论文  OAI收割 CHEMOSPHERE, 2022, 卷号: 308, 页码: 136465-1-10 作者:  Liu, Wang;  Zhang, Jiye;  Liang, Xuefang;  Wang, Yuchen;  Liu, Ruimin   |  收藏  |  浏览/下载：11/0  |  提交时间：2023/02/06 2  4-DTBP  Immunotoxicity  Anti-Inflammation  Intestinal barrier  NF-?B pathway   Design, Synthesis, and Biological Evaluation of IRAK4-Targeting PROTACs 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 1, 页码: 82-87 作者:  Chen, Yun;  Ning, Yi;  Bai, Gang;  Tong, Linjiang;  Zhang, Tao   |  收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 IRAK4  PROTAC  protein degrader  scaffolding role  diffuse large B-cell lymphoma   Cloning and functional characterization of IRAK1 from rainbow trout (Oncorhynchus mykiss) 期刊论文  OAI收割 DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 114, 页码: 8 作者:  Yue Cong Yang;  Shan Nan Chen;  Gan, Zhen;  Huang, Lin;  Nie, P.   |  收藏  |  浏览/下载：84/0  |  提交时间：2020/12/31 IRAK1  NF-kappa B  MyD88  IRAK4  TRAF6  Rainbow trout   Genome-wide small RNA profiling reveals tiller development in tall fescue (Festuca arundinacea Schreb) 期刊论文  OAI收割 BMC GENOMICS, 2020, 卷号: 21, 期号: 1, 页码: 13 作者:  Hu, Tao;  Wang, Tao;  Li, Huiying;  Wassie, Misganaw;  Xu, Huawei   |  收藏  |  浏览/下载：30/0  |  提交时间：2020/10/04 MicroRNAs  Tiller development  Small RNA deep sequencing  Stem-loop qRT-PCR  Tall fescue   Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14 作者:  Chen, Yun;  Bai, Gang;  Ning, Yi;  Cai, Shi;  Zhang, Tao   |  收藏  |  浏览/下载：40/0  |  提交时间：2020/07/01 lnterleukin-1 receptor associated kinase 4  Imidazol1,2-6]pyridazine  Diffuse large B-cell lymphoma  Drug design  Antitumor agents   Mechanistic molecular responses of the giant clam Tridacna crocea to Vibrio coralliilyticus challenge 期刊论文  OAI收割 PLOS ONE, 2020, 卷号: 15, 期号: 4, 页码: e0231399 作者:  Xu, Duo;  Zhao, Zehui;  Zhou, Zihua;  Lin, Yue;  Zhang, Xiangyu   |  收藏  |  浏览/下载：146/0  |  提交时间：2020/09/22 Three new compounds with nitric oxide inhibitory activity from Tirpitzia sinensis, an ethnomedicinal plant from Southwest China 期刊论文  OAI收割 BMC CHEMISTRY, 2019, 卷号: 13, 页码: 12 作者:  Gu, Ronghui;  Wang, Yuehu;  Wu, Shibiao;  Wang, Yeling;  Li, Ping   |  收藏  |  浏览/下载：72/0  |  提交时间：2019/07/29 Tirpitzia sinensis  Linaceae  Lignans  Inflammatory  NO inhibition  Pharmacological targets  Pharmacophore  In silico   Molecular characterization of Pacific oyster (Crassostrea gigas) IRAK4 gene and its role in MyD88-dependent pathway 期刊论文  OAI收割 DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 卷号: 72, 页码: 21-29 作者:  Tang, Xueying;  Huang, Baoyu;  Zhang, Linlin;  Li, Li;  Zhang, Guofan   |  收藏  |  浏览/下载：33/0  |  提交时间：2017/09/29 Crassostrea Gigas  Irak4  Myd88  Tlr  Nf-kappa b