中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [12]
昆明动物研究所 [6]
大连化学物理研究所 [5]
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期刊论文 [31]
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2022 [1]
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物理化学 [2]
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SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/06/15
Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
期刊论文
OAI收割
ONCOGENESIS, 2021, 卷号: 10
作者:
Fan, Xiaoqing
;
Fan, Junqi
;
Yang, Haoran
;
Zhao, Chenggang
;
Niu, Wanxiang
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/29
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
OAI收割
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13
作者:
Wang, Zheng
;
Li, Zeng-xia
;
Zhao, Wen-cao
;
Huang, Hong-bo
;
Wang, Jia-qi
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
grincamycin B
marine natural product
isocitrate dehydrogenase 1
apoptosis
ER stress
intracellular ROS
Zebrafish embryos
hematological malignancies
Licochalcone A suppresses the proliferation of sarcoma HT-1080 cells, as a selective R132C mutant IDH1 inhibitor
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 5
作者:
Hu, Chujiao
;
Zuo, Yu
;
Liu, Jingqiu
;
Xu, Heng
;
Liao, Weike
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Licochalcone A
Mutant IDH1
Selective inhibitor
Flavipesines A and B and Asperchalasines E-H: Cytochalasans and Merocytochalasans from Aspergillus flavipes
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 11, 页码: 2994-3001
作者:
Zhang, Xiaotian
;
Yang, Lu
;
Wang, Wenjing
;
Wu, Zhaodi
;
Wang, Jianping
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收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/03/18
Pharmacological characterization of TQ05310, a potent inhibitor of isocitrate dehydrogenase 2 R140Q and R172K mutants
期刊论文
OAI收割
CANCER SCIENCE, 2019, 页码: 9
作者:
Gao, Mingzhao
;
Zhu, Hongmei
;
Fu, Li
;
Li, Yun
;
Bao, Xubin
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
AG-221
IDH2
leukemia
R140Q
R172K
Discovery of DC_H31 as potential mutant IDH1 inhibitor through NADPH-based high throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3229-3236
作者:
Duan, Zhe
;
Liu, Jingqiu
;
Niu, Liping
;
Wang, Jun
;
Feng, Mingqian
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/07/01
IDH1 mutation
High-throughput screening
Pan-inhibitor
2-HG
Gliomas
A radiomics nomogram may improve the prediction of IDH genotype for astrocytoma before surgery
期刊论文
OAI收割
EUROPEAN RADIOLOGY, 2019, 卷号: 29, 期号: 7, 页码: 3325-3337
作者:
Tan, Yan
;
Zhang, Shuai-tong
;
Wei, Jing-wei
;
Dong, Di
;
Wang, Xiao-chun
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2019/07/11
Astrocytoma
Radiomics
Nomogram
Isocitrate dehydrogenase
Survival