中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [14]
西北高原生物研究所 [10]
大连化学物理研究所 [10]
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Metabolic-related gene pairs signature analysis identifies ABCA1 expression levels on tumor-associated macrophages as a prognostic biomarker in primary IDHWT glioblastoma
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13
作者:
Wang, Shiqun
;
Li, Lu
;
Zuo, Shuguang
;
Kong, Lingkai
;
Wei, Jiwu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/12/22
primary glioblastoma
wild-type isocitrate dehydrogenase
metabolic-related gene pairs
prognosis
tumor-associated macrophages
ABCA1
SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 21
作者:
Wang, Xiaomin
;
Chen, Ziqi
;
Xu, Jun
;
Tang, Shuai
;
An, Nan
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/06/15
Promotion of Carbon Dioxide Biofixation through Metabolic and Enzyme Engineering
期刊论文
OAI收割
CATALYSTS, 2022, 卷号: 12, 期号: 4, 页码: 17
作者:
Pu, Xin
;
Han, Yejun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/15
carbon dioxide biofixation
carboxylases
enzyme engineering
metabolic engineering
artificial carbon fixation pathway
盐度对重金属镉的毒性影响:以太平洋牡蛎为例
期刊论文
OAI收割
生态毒理学报, 2022, 卷号: 17, 期号: 2, 页码: 299-310
作者:
王智宇
;
姜爱莉
;
吉成龙
;
吴惠丰
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/01/26
镉
低盐
太平洋牡蛎
离子平衡
氧化应激
能量代谢
Heterogeneity of subsets in glioblastoma mediated by Smad3 palmitoylation
期刊论文
OAI收割
ONCOGENESIS, 2021, 卷号: 10
作者:
Fan, Xiaoqing
;
Fan, Junqi
;
Yang, Haoran
;
Zhao, Chenggang
;
Niu, Wanxiang
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/11/29
Synthesis and Evaluation of 3-(Indol-3-yl)-4-(Pyrazolo[3,4-c]Pyridazin-3-yl)-Maleimides as Potent Mutant Isocitrate Dehydrogenase-1 Inhibitors
期刊论文
OAI收割
PHARMACEUTICAL CHEMISTRY JOURNAL, 2021, 卷号: 55, 期号: 7, 页码: 655-664
作者:
Xu, Jianghong
;
Hu, Yuanyuan
;
Liu, Xiaoqi
;
Gao, Anhui
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2021/12/01
IDH1-R132H inhibitors
synthesis
biological activity
docking
3-(indol-3-yl)-4-(pyrazolo-[3
4-c]pyridazin-3-yl)-maleimides
Isocitrate Dehydrogenase 2 Inhibitors for the Treatment of Hematologic Malignancies: Advances and Future Opportunities
期刊论文
OAI收割
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21
作者:
Huang, Feng
;
Tian, Tian
;
Wu, Yizhe
;
Che, Jinxin
;
Yang, Haiyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/06/15
Isocitrate dehydrogenase 2
IDH2
mutant
inhibitors
structure-activity relationship
blood cance
Reprogramming the immunosuppressive microenvironment of IDH1 wild-type glioblastoma by blocking Wnt signaling between microglia and cancer cells
期刊论文
OAI收割
ONCOIMMUNOLOGY, 2021, 卷号: 10, 期号: 1, 页码: 13
作者:
Fan, Dandan
;
Yue, Qi
;
Chen, Jian
;
Wang, Cong
;
Yu, Ruilin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2021/08/17
Wnt/beta-catenin
IDH1-wildtype glioblastoma
Microglia
Phenotypic polarization
Discovery of Novel IDH1 Inhibitor Through Comparative Structure-Based Virtual Screening
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 11
作者:
Wang, Yuwei
;
Tang, Shuai
;
Lai, Huanling
;
Jin, Ruyi
;
Long, Xu
  |  
收藏
  |  
浏览/下载:52/0
  |  
提交时间:2020/12/24
IDH1
gliomas
molecular docking
virtual screening
docking-based virtual screening
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 203, 页码: 19
作者:
Che, Jinxin
;
Huang, Feng
;
Zhang, Mengmeng
;
Xu, Gaoya
;
Qu, Bingxue
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/21
Metabolic pathways
Isocitrate dehydrogenase 2
Conformational restriction
Macrocyclic derivatives
Inhibitors