中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [51]
上海生物化学与细胞... [28]
合肥物质科学研究院 [26]
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期刊论文 [261]
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From bench to bedside: current development and emerging trend of KRAS-targeted therapy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 18
作者:
Chen, Yi
;
Liu, Qiu-pei
;
Xie, Hua
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
KRAS mutation
KRAS(G12C) inhibitor
Pan-KRAS inhibitor
SHP2 allosteric inhibitor
SOS1 inhibitor
combination therapy
Monomeric compounds from traditional Chinese medicine: New hopes for drug discovery in pulmonary fibrosis
期刊论文
OAI收割
BIOMEDICINE & PHARMACOTHERAPY, 2023, 卷号: 159, 页码: 16
作者:
Wang, Qi
;
Li, Wenjun
;
Hu, Haibo
;
Lu, Xuechao
;
Qin, Song
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/11/15
Pulmonary fibrosis
Monomeric compounds
Flavonoids
Alkaloid
Terpenoids
Phenols
Saponins
Quinones
Diesel exhaust PM2.5 greatly deteriorates fibrosis process in pre-existing pulmonary fibrosis via ferroptosis
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2023, 卷号: 171, 页码: 17
作者:
Yue, Dayong
;
Zhang, Qian
;
Zhang, Jinjin
;
Liu, Weili
;
Chen, Libang
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/08/17
PM2
5
Pulmonary fibrosis
HO-1
Ferritinophagy
Ferroptosis
Mannosylated engineered trichosanthin-legumain protein vaccine hydrogel for breast cancer immunotherapy
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 223, 页码: 1485-1494
作者:
Chen, Guihua
;
Xiong, Wei
;
Gu, Zeyun
;
Gao, Yanrong
;
Hou, Jiazhen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/17
Engineered protein
Hydrogel
Cancer vaccine
Trichosanthin
Legumain
Post-surgery
Macrophage Membrane-Coated Nano- Gemcitabine Promotes Lymphocyte Infiltration and Synergizes AntiPD-L1 to Restore the Tumoricidal Function
期刊论文
OAI收割
ACS NANO, 2022, 页码: 15
作者:
Li, Jie
;
Wu, Yao
;
Wang, Jiaoying
;
Xu, Xiaoxuan
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/04/10
gemcitabine
macrophage
nanoparticle
lymphocytes infiltration
immunotherapy
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
OAI收割
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
The Rostral Ventromedial and Lateral Medulla Are the Major Areas Responsive to Lung Cancer Progression among Brainstem Lung-Innervating Nuclei
期刊论文
OAI收割
BRAIN SCIENCES, 2022, 卷号: 12
作者:
Chen, Mo
;
Jiao, Yingfu
;
Shi, Yumiao
;
Xu, Saihong
;
Tang, Dan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/23
lung cancer
brain-lung axis
crosstalk
brainstem nuclei
vagal core
c-Fos
pseudorabies virus
retrograde tracing
neural circuit
Too depressed to breathe: The longitudinal association between depressive symptoms and lung function among general middle-aged and older adults
期刊论文
OAI收割
ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2022, 卷号: 103, 页码: 5
作者:
Guo, Lizhi
;
Yang, Li
;
Rao, Liwei
;
Luo, Fengping
;
Gao, Ningcan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/11/21
Depressive symptoms
Lung function
Peak expiratory flow (PEF)
General middle-aged and older adults
Neoadjuvant immunotherapy in non-small-cell lung cancer: a narrative review on mechanisms, efficacy and safety
期刊论文
OAI收割
JOURNAL OF THORACIC DISEASE, 2022
作者:
Shao, Lan
;
Lou, Guangyuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/22
Neoadjuvant
immunotherapy
immune-checkpoint inhibitors
non-small cell lung cancer (NSCLC)
Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18
作者:
Sun, Yaoliang
;
Zhang, Ying
;
Chen, Xiaoai
;
Yu, Aisong
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/30
NSD3
PROTAC
Degrader
Methyltransferase