机构

• 上海药物研究所 [13]
• 新疆理化技术研究所 [1]
• 昆明植物研究所 [1]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [16]

内容类型

• 期刊论文 [16]

发表日期

• 2023 [2]
• 2022 [1]
• 2021 [5]
• 2020 [1]
• 2019 [3]
• 2018 [1]
• 更多

学科主题

• Oncology [1]

筛选

浏览/检索结果: 共16条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Selective degradation of cellular BRD3 and BRD4-L promoted by PROTAC molecules in six cancer cell lines 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 17 作者:  Yan, Ziqin;  Lyu, Xilin;  Lin, Dongze;  Wu, Gaoxing;  Gong, Yang   |  收藏  |  浏览/下载：24/0  |  提交时间：2023/10/17 Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：18/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis   Design, synthesis and biological evaluation of sulfonamides inhibitors of XPO1 displaying activity against multiple myeloma cells 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 235 作者:  Qu, Bingxue;  Xu, Yongjin;  Lu, Yang;  Zhuang, Weihao;  Jin, Xinxin   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/12/23 XPO1  Multiple myeloma  MM.1S  N-phenylsulfonamide  Oral administration   Design, Synthesis, and Biological Evaluation of HDAC Degraders with CRBN E3 Ligase Ligands 期刊论文  OAI收割 MOLECULES, 2021, 卷号: 26, 期号: 23, 页码: 19 作者:  Lu, Yingxin;  Sun, Danwen;  Xiao, Donghuai;  Shao, Yingying;  Su, Mingbo   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/06/15 HDAC degraders  CRBN ligands  proteins of interest  benzyl alcohol linkage   Development of peptide epoxyketones as selective immunoproteasome inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 221, 页码: 113556 作者:  Li, Xuemei;  Hong, Duidui;  Zhang, Mengmeng;  Xu, Lei;  Zhou, Yubo   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21 Epoxyketones  Immunoproteasome inhibitor  Selectivity  Multiple myeloma   Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng   |  收藏  |  浏览/下载：67/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 29, 页码: 14 作者:  Zhao, Yanmei;  Xu, Lei;  Zhang, Jiankang;  Zhang, Mengmeng;  Lu, Jingyi   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/05/24 Proteasome inhibitor  Piperidine  Peptidyl  Anti-cancer  SAR   Design, synthesis and biological evaluation of thioether-containing lenalidomide and pomalidomide derivatives with anti-multiple myeloma activity 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 13 作者:  Wang, Yuhong;  Mi, Tian;  Li, Yiming;  Kan, Weijuan;  Xu, Gaoya   |  收藏  |  浏览/下载：15/0  |  提交时间：2021/05/24 Lenalidomide  Multiple myeloma  MM.1S  Late-stage sulfuration   Design and synthesis of new lenalidomide analogs via Suzuki cross-coupling reaction 期刊论文  OAI收割 ARCHIV DER PHARMAZIE, 2020, 页码: 10 作者:  Xiao, Donghuai;  Wang, Yu-jie;  Wang, Han-lin;  Zhou, Yu-bo;  Li, Jia   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/07/01 antitumor  arylboronic acid  lenalidomide  Suzuki cross-coupling   Structure-Based Discovery and Development of a Series of Potent and Selective Bromodomain and Extra-Terminal Protein Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 18, 页码: 8642-8663 作者:  Hu, Jianping;  Tian, Chang-Qing;  Damaneh, Mohammadali Soleimani;  Li, Yanlian;  Cao, Danyan   |  收藏  |  浏览/下载：34/0  |  提交时间：2020/07/01