中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [85]
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期刊论文 [339]
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The novel norcantharidin derivative DCZ5417 suppresses multiple myeloma progression by targeting the TRIP13-MAPK-YWHAE signaling pathway
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 17
作者:
Wang, Yingcong
;
Dong, Sanfeng
;
Hu, Ke
;
Xu, Li
;
Feng, Qilin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Norcantharidin
Derivative
DCZ5417
TRIP13
Anti-myeloma
MAPK
Proteasome inhibitors reduce CD73 expression partly
via
decreasing p-ERK in NSCLC cells
期刊论文
OAI收割
LIFE SCIENCES, 2023, 卷号: 332, 页码: 10
作者:
Su, Ai-Ling
;
Tian, Chang-Qing
;
Ou, Ying-Jie
;
Bao, Xu-Bin
;
Huan, Xia-Juan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
CD73
Proteasome inhibitors
ERK
NSCLC
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Integrated analysis of a miRNA-mRNA network related to immunity and autophagy in Macrobrachium rosenbergii infected with Aeromonas hydrophila
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
作者:
Wang, Feifei
;
Zhao, Fei
;
Tan, Aiping
;
Deng, Yuting
;
Wang, Ling
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/30
Macrobrachium rosenbergii
miRNA-mRNA
Immunity
Autophagy
Aeromonas hydrophila
A zinc-modified
Anemarrhena asphodeloides
polysaccharide complex enhances immune activity
via
the NF-?B and MAPK signaling pathways
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2023, 卷号: 249, 页码: 12
作者:
Zhang, Shaojie
;
Zhang, Qian
;
Li, Chong
;
Xing, Na
;
Zhou, Pengfei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Anemarrhena asphodeloides Bunge
Zinc modification
Immunoregulatory activity
Zebrafish
NF-kappa B signaling pathway
MAPKs signaling pathway
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Whole-Genome Re-sequencing and Transcriptome Reveal Candidate Genes and Pathways Associated with Hybrid Sterility in Hermaphroditic Argopecten Scallops
期刊论文
OAI收割
MARINE BIOTECHNOLOGY, 2023, 页码: 16
作者:
Yu, Tieying
;
Ning, Junhao
;
Wang, Fukai
;
Liu, Guilong
;
Wang, Quanchao
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/11/15
Hermaphroditic Argopecten scallops
Hybrid sterility
Gametogenesis
Meiosis and mitosis
Apoptosis
Unraveling the Therapeutic Mechanism of Saussurea involucrata against Rheumatoid Arthritis: A Network Pharmacology and Molecular Modeling-Based Investigation
期刊论文
OAI收割
NUTRIENTS, 2023, 卷号: 15, 期号: 19
作者:
Chen, Jinghua
;
Wu, Xiaoke
;
Yu, Ruitao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2023/12/01
Hepatoprotective Mechanism and Material Basis of Swertia Plants Based On Network Pharmacology and Molecular Docking Method
期刊论文
OAI收割
LATIN AMERICAN JOURNAL OF PHARMACY, 2023, 卷号: 42, 期号: 2, 页码: 374
作者:
Huang, Xian-Ju
;
Liu, Shi-Quan
;
Dai, Jia-Wei
;
LI, Tian-Cai
;
Wu, Zhou-Yang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/01
The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization