中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Eliminating drug target interference with specific antibody or its F(ab′)
2
fragment in the bridging immunogenicity assay
期刊论文
OAI收割
BIOANALYSIS, 2024, 页码: 14
作者:
Deng, Xiaojie
;
Hou, Yingying
;
Yuan, Wenyi
;
Yang, Hongzhou
;
Guo, Ruowen
  |  
收藏
  |  
浏览/下载:134/0
  |  
提交时间:2024/04/09
anti-drug antibody
IgE
immunogenicity
mitigation
target interference
Development and Validation of an ADA-Tolerant Assay for Quantification of an Exatecan-Based ADC in Monkey Plasma
期刊论文
OAI收割
MOLECULES, 2024, 卷号: 29, 期号: 3, 页码: 14
作者:
Tao, Yimin
;
Lu, Wei
;
Gao, Jinli
;
Yang, Shuangshuang
;
Ruan, Chaoyi
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/13
antibody-drug conjugate (ADC)
bioanalysis
anti-drug antibody (ADA)
ligand binding assay (LBA)
ADA-tolerant assay
Metabolite characterisation of the peptide-drug conjugate LN005 in liver S9s by UHPLC-Orbitrap-HRMS
期刊论文
OAI收割
XENOBIOTICA, 2024, 页码: 9
作者:
Yuan, Yali
;
Wang, Weiqiang
;
Luo, Jing
;
Tang, Chongzhuang
;
Zheng, Yuandong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
peptide-drug conjugate
PDC
LN005
metabolite identification
liver S9s
An ultra-compact promoter drives widespread neuronal expression in mouse and monkey brains
期刊论文
OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 11, 页码: 21
作者:
Wang, Jingyi
;
Lin, Jianbang
;
Chen, Yefei
;
Liu, Jing
;
Zheng, Qiongping
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/01/16
A validated LC-MS/MS method for the quantification of bevacizumab in rat, cynomolgus monkey, and human serum
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2023, 卷号: 235, 页码: 11
作者:
Zhou, Ainan
;
Yu, Jinghua
;
Wu, Yali
;
Xue, Hao
;
Zhong, Dafang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Monoclonal antibody
Bevacizumab
LC-MS
MS
Surrogate peptide
Pharmacokinetics
Serum
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for Treatment of Nectin-4-expressing Cancers
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2023, 卷号: 22, 期号: 8, 页码: 913-925
作者:
Zhou, Wei
;
Fang, Peng
;
Yu, Dongan
;
Ren, Hongyuan
;
You, Meng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
Abnormality of anxious behaviors and functional connectivity between the amygdala and the frontal lobe in maternally deprived monkeys
期刊论文
OAI收割
BRAIN AND BEHAVIOR, 2023, 页码: 10
作者:
Feng, Xiao-Li
;
Wang, Jiao-Jian
;
Wu, Jing
;
Ren, Xiao-Feng
;
Zhou, Hui
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/17
amygdala-prefrontal connection
anxious behaviors
brain circuits
maternal deprivation
rhesus monkeys
Dynamic evolution of the anterior cingulate-insula network during seizures
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2023, 页码: 12
作者:
Yang, Yujiao
;
Chen, Dong
;
Wang, Jing
;
Wang, Jie
;
Yan, Zhaofen
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/10/09
anterior cingulate cortex
epilepsy
excitation-inhibition ratio
functional connectivity
insula
Development, Validation and Application of a Bridging ELISA for Detection of Antibodies against GQ1001 in Cynomolgus Monkey Serum
期刊论文
OAI收割
MOLECULES, 2023, 卷号: 28, 期号: 4, 页码: 1684
作者:
Liu, Tingting
;
Sun, Yajun
;
Deng, Xiaojie
;
Shi, Lili
;
Chen, Wenyi
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
antibody-drug conjugate
immunogenicity
anti-drug antibody
bridging ELISA
CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1
作者:
Li, Bang
;
Zhao, Hui
;
Tu, Zhuchi
;
Yang, Weili
;
Han, Rui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/05/31