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Discovery of novel dual RAGE/SERT inhibitors for the potential treatment of the comorbidity of Alzheimer's disease and depression

 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 236, 页码: 17
作者:  Zhang, Chao;  Wang, Lan;  Xu, Yixiang;  Huang, Yunyuan;  Huang, Junyang
  |  收藏  |  浏览/下载：30/0  |  提交时间：2022/08/16
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 229, 页码: 22
作者:  Li, Xiaokang;  Li, Jinwen;  Huang, Yunyuan;  Gong, Qi;  Fu, Yan
  |  收藏  |  浏览/下载：31/0  |  提交时间：2022/06/15
Twin drug design, synthesis and evaluation of diosgenin derivatives as multitargeted agents for the treatment of vascular dementia 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 37, 页码: 16
作者:  Yang, Gui-Xiang;  Sun, Jia-Min;  Zheng, Lu-Lu;  Zhang, Li;  Li, Jie
  |  收藏  |  浏览/下载：23/0  |  提交时间：2021/06/11
Mulberry Diels-Alder-type adducts from Morus alba as multi-targeted agents for Alzheimer's disease 期刊论文  OAI收割
PHYTOCHEMISTRY, 2019, 卷号: 157, 期号: x, 页码: 82-91
作者:  Xia, Chun-Li;  Tang, Gui-Hua;  Guo, Yan-Qiong;  Xu, You-Kai;  Huang, Zhi-Shu
  |  收藏  |  浏览/下载：65/0  |  提交时间：2019/04/22
Design, synthesis and biological evaluation of novel dual inhibitors of acetylcholinesterase and beta-secretase 期刊论文  OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 卷号: 17, 期号: 4, 页码: 1600-1613
作者:  Zhu, Yiping;  Xiao, Kun;  Ma, Lanping;  Xiong, Bin;  Fu, Yan
  |  收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08
AD  AChE  BACE-1  Dual inhibitor  HE  HMC  HEA