中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [37]
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Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Deng, Minjie
;
Gao, Yue
;
Wang, Peipei
;
Du, Wenjing
;
Xu, Gaoya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Han-lin
;
Li, Jia-nan
;
Kan, Wei-juan
;
Xu, Gao-ya
;
Luo, Guang-hao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
acute myeloid leukemia
cytarabine
daunorubicin
idarubicin
drug resistant
multi-omics
autophagy
chloroquine phosphate
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
Guo, Siqi
;
Jia, Tongguan
;
Xu, Xiaoming
;
Yang, Feng
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390
作者:
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
期刊论文
OAI收割
CELL RESEARCH, 2022, 页码: 19
作者:
Hu, Cheng-Long
;
Chen, Bing-Yi
;
Li, Zijuan
;
Yang, Tianbiao
;
Xu, Chun-Hui
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/12/13
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 18
作者:
Cao, Yu
;
Tu, Yutong
;
Fu, Liping
;
Yu, Qian
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
Metabolism
Design
Proteasome inhibitors
Non-covalent
Multiple myeloma
Identification of 2-Aminopyrimidine Derivatives as FLT3 Kinase Inhibitors with High Selectivity over c-KIT
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 3229-3248
作者:
Tong, Lexian
;
Wang, Peipei
;
Li, Xuemei
;
Dong, Xiaowu
;
Hu, Xiaobei
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/08/16
Effect of donor characteristics on T cell-replete haploidentical stem cell transplantation over the last 10 years at a single institution
期刊论文
OAI收割
BRITISH JOURNAL OF HAEMATOLOGY, 2021
作者:
Wu, Yibo
;
Lai, Xiaoyu
;
Shi, Jimin
;
Tan, Yamin
;
Zhao, Yanmin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/10
haploidentical
haematopoietic stem cell transplantation
donor selection
donor characteristics
donor age
female to male
Oridonin inhibits DNMT3A R882 mutation-driven clonal hematopoiesis and leukemia by inducing apoptosis and necroptosis
期刊论文
OAI收割
CELL DEATH DISCOVERY, 2021, 卷号: 7, 期号: 1, 页码: 12
作者:
Liao, Min
;
Dong, Qiongye
;
Chen, Ruiqing
;
Xu, Liqian
;
Jiang, Yuxuan
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/12/01