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浏览/检索结果: 共753条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18 作者:  Zhuo, Ning;  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Yin, Jianpeng   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/25 Type 2 Diabetes  TGR5 agonist  Betulinic acid  Gut-restricted  Gallbladder-filling effects  Kinetophores   Fucoxanthin Alleviates Dextran Sulfate Sodium-Induced Colitis and Gut Microbiota Dysbiosis in Mice 期刊论文  OAI收割 JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2024, 卷号: 72, 期号: 8, 页码: 4142-4154 作者:  Yang, Yu-Hong;  Chen, Chen;  Zheng, Yan;  Wu, Zi-Jian;  Zhou, Meng-Qing   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/04/07 fucoxanthin  colitis  intestinal barrier function  anti-inflammation  antioxidation  gut microbiota   Xuanbai Chengqi Decoction alleviates acute lung injury by inhibiting NLRP3 inflammasome 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2024, 卷号: 319, 页码: 13 作者:  Wang, Shun;  Lin, Feifei;  Zhang, Chengxi;  Gao, Dan;  Qi, Zhuocao   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/12/08 Xuanbai Chengqi Decoction  Acute lung injury  NLRP3 inflammasome  Pyroptosis   Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21 作者:  Zhang, Hongjin;  Lin, Guohao;  Jia, Suyun;  Zhang, Ying;  Wu, Jianbo   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/01/26 Thieno[3  d ]pyrimidine derivative  Cyclin-dependent kinase 7  Small molecule inhibitor  Kinome selectivity  Triple negative breast cancer   Development and validation of a sensitive liquid chromatography-tandem mass spectrometry method for the assay of 12 substances in rat plasma and its application to rat pharmacokinetics of Epimedium and Psoraleae Fructus herb pair after oral administration 期刊论文  OAI收割 JOURNAL OF SEPARATION SCIENCE, 2024, 卷号: 47, 期号: 1, 页码: 17 作者:  Wang, Linwei;  Yin, Xiaoying;  Liu, Huan;  Wang, Yangyang;  Li, Zhixiong   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/02/27 compatibility behaviors  Epimedium  LC-MS/MS  pharmacokinetics  Psoraleae Fructus   Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12 作者:  Song, Zhaoxiang;  Lu, Dan;  Sun, Jun;  Ye, Yangliang;  Fang, Jiahui   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/01/16 GPR35  IBD  Lodoxamide   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   Rational design of oral delivery nanosystems for hypoglycemic peptides 期刊论文  OAI收割 NANO TODAY, 2023, 卷号: 53, 页码: 19 作者:  Peng, Taoxing;  Shao, Xinyue;  Long, Li;  Liu, Han;  Song, Wenqin   |  收藏  |  浏览/下载：21/0  |  提交时间：2024/01/16 Hypoglycemic peptides  Oral delivery  Mucus penetration  Endocytosis  Intracellular trafficking  Exocytosis   Pharmacokinetic and metabolite profile of orally administered anemoside B4 in rats with an improved exposure in formulations of rectal suppository 期刊论文  OAI收割 JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 315, 页码: 11 作者:  Ye, Yaqing;  Xue, Mingzhen;  Tian, Xiaoting;  Gao, Hongwei;  Hu, Pei   |  收藏  |  浏览/下载：10/0  |  提交时间：2023/10/17 Anemoside B4  Pulsatilla chinensis  metabolite identification  Pharmacokinetics  Rectal suppository   Cyclodextrin MOFs modified dry powder inhalers quadruple bioavailability of luteolin to ameliorate fibrosing interstitial lung disease 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 645, 页码: 9 作者:  Ren, Xiaohong;  Yang, Ting;  Zhang, Kaikai;  Liu, Yujie;  Wang, Caifen   |  收藏  |  浏览/下载：6/0  |  提交时间：2023/12/08 Fibrosing interstitial lung disease  Luteolin  Cyclodextrin metal -organic frameworks  Dry powder inhalers