中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共19条,第1-10条 帮助

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应用鞣花酸治疗亨廷顿舞蹈病转基因小鼠的研究 学位论文  OAI收割
: 中国科学院大学, 2020
作者:  
孙勋
  |  收藏  |  浏览/下载:27/0  |  提交时间:2021/09/07
Ellagic acid rescues motor and cognitive deficits in the R6/2 mouse model of Huntington's disease by lowering mutant huntingtin protein 期刊论文  OAI收割
FOOD & FUNCTION, 2020, 卷号: 11, 期号: 2, 页码: 1334-1348
作者:  
Sun, Xun;  Zhu, Jie;  Sun, Xiao-ying;  Ji, Mei;  Yu, Xiao-lin
  |  收藏  |  浏览/下载:22/0  |  提交时间:2020/05/06
Intravenous immunoglobulin ameliorates motor and cognitive deficits and neuropathology in R6/2 mouse model of Huntington's disease by decreasing mutant huntingtin protein level and normalizing NF-kappa B signaling pathway 期刊论文  OAI收割
BRAIN RESEARCH, 2018, 卷号: 1697, 页码: 21-33
作者:  
Liu, Shu-ying;  Yu, Xiao-lin;  Zhu, Jie;  Liu, Xiang-meng;  Zhang, Yue
  |  收藏  |  浏览/下载:46/0  |  提交时间:2018/10/11
Targeting Gpr52 lowers mutant HTT levels and rescues Huntington's disease-associated phenotypes 期刊论文  OAI收割
BRAIN, 2018, 卷号: 141, 页码: 1782-1798
作者:  
Song, Haikun;  Li, Hexuan;  Guo, Shimeng;  Pan, Yuyin;  Fu, Yuhua
  |  收藏  |  浏览/下载:50/0  |  提交时间:2019/01/08
PolyQ-expanded huntingtin and ataxin-3 sequester ubiquitin adaptors hHR23B and UBQLN2 into aggregates via conjugated ubiquitin 期刊论文  OAI收割
FASEB JOURNAL, 2018, 卷号: 32, 期号: 6, 页码: 2923-2933
作者:  
Yang, Hui;  Yue, Hong-Wei;  He, Wen-Tian;  Hong, Jun-Ye;  Jiang, Lei-Lei
  |  收藏  |  浏览/下载:26/0  |  提交时间:2019/04/28
PolyQ 2.0: an improved version of PolyQ, a database of human polyglutamine proteins 期刊论文  OAI收割
DATABASE-THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION, 2016
作者:  
Li, Chen;  Nagel, Jeremy;  Androulakis, Steve;  Song, Jiangning;  Buckle, Ashley M.
收藏  |  浏览/下载:86/0  |  提交时间:2017/03/13
Critical evaluation of in silico methods for prediction of coiled-coil domains in proteins 期刊论文  OAI收割
BRIEFINGS IN BIOINFORMATICS, 2016, 卷号: 17, 期号: 2, 页码: 270-282
作者:  
Li, Chen;  Chang, Catherine Ching Han;  Nagel, Jeremy;  Porebski, Benjamin T.;  Hayashida, Morihiro
收藏  |  浏览/下载:36/0  |  提交时间:2017/03/13
Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology 期刊论文  OAI收割
SCIENTIFIC REPORTS, 2014, 卷号: 4, 期号: 1, 页码: 6410-6410
作者:  
Yang, H;  Li, JJ;  Liu, S;  Zhao, J;  Jiang, YJ
收藏  |  浏览/下载:34/0  |  提交时间:2015/07/22
Autoinhibitory Structure of the WW Domain of HYPB/SETD2 Regulates Its Interaction with the Proline-Rich Region of Huntingtin 期刊论文  OAI收割
STRUCTURE, 2014, 卷号: 22, 期号: 3, 页码: 378-386
作者:  
Gao, YG;  Yang, H;  Zhao, J;  Jiang, YJ;  Hu, HY
收藏  |  浏览/下载:19/0  |  提交时间:2015/07/22
Genome-wide loss of 5-hmC is a novel epigenetic feature of Huntingtons disease 期刊论文  OAI收割
HUMAN MOLECULAR GENETICS, 2013, 卷号: 22, 期号: 18, 页码: 3641-3653
作者:  
Wang, Fengli;  Yang, Yeran;  Lin, Xiwen;  Wang, Jiu-Qiang;  Wu, Yong-Sheng
收藏  |  浏览/下载:36/0  |  提交时间:2013/10/16