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The Tyrosine Kinase Inhibitor Bafetinib Inhibits PAR2-induced Activation of TRPV4 In Vitro and Pain In Vivo1
期刊论文
OAI收割
出版物, 2111, 页码: 1-44
作者:
1M S Grace
;
T Lieu
;
B Darby
;
F C Abogadie
;
N Veldhuis N W Bunnett
;
P McIntyre
  |  
收藏
  |  
浏览/下载:213/0
  |  
提交时间:2017/07/24
Transient Receptor Potential Ion Channel
Trpv4
Protease Activated Receptor
Par2
Pain
Tyrosine Kinase
Bafetinib
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2
期刊论文
OAI收割
STEROIDS, 2024, 卷号: 202, 页码: 8
作者:
Liu, Yaowen
;
Nie, Tianqing
;
Hou, Jinjun
;
Long, Huali
;
Zhang, Zijia
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/13
3CLpro
SARS-CoV-2
Betulinic acid
Natural product
Inhibitory activity
Extracellular Matrix-Trapped Bioinspired Lipoprotein Prolongs Tumor Retention to Potentiate Antitumor Immunity
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 14
作者:
Wu, Yao
;
Li, Yongping
;
Hu, Zixin
;
Li, Yuan
;
Zhang, Shixuan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/02/27
antitumor responses
bioinspired lipoprotein
extracellular matrix
pomalidomide
tumor retention
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13
作者:
Zeng, Yue
;
Shi, Wei
;
Liu, Zhi
;
Xu, Hao
;
Liu, Liya
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/02/19
Deubiquitylating Enzymes in Cancer and Immunity
期刊论文
OAI收割
ADVANCED SCIENCE, 2023, 页码: 37
作者:
Ren, Jiang
;
Yu, Peng
;
Liu, Sijia
;
Li, Ran
;
Niu, Xin
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/08
cancer
deubiquitylating enzymes (DUBs)
immunity
therapeutic approach
Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Jiang, Xiangrui
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/25
Assessment of the structure-activity relationship and antileukemic activity of diacylpyramide compounds as human ClpP agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 258, 页码: 17
作者:
Zhang, Ranran
;
Wang, Pengyu
;
Wei, Bingyan
;
Chen, Liang
;
Song, Xiaomin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
ClpP agonists
Structure-activity relationship
Mitochondrial respiratory chain
Antileukemic therapy
Therapeutic potential of enzymatically extracted eumelanin from squid ink in type 2 diabetes mellitus ICR mice: Multifaceted intervention against hyperglycemia, oxidative stress and depression
期刊论文
OAI收割
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2023, 页码: 15
作者:
Song, Wen
;
Xing, Ronge
;
Yang, Haoyue
;
Liu, Song
;
Yu, Huahua
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/11/30
type 2 diabetes mellitus (T2DM)
eumelanin
hypoglycemic activity
antioxidant activity
antidepressant activity
Expression patterns and antifungal function study of KaSPI in
Mythimna separata
期刊论文
OAI收割
BULLETIN OF ENTOMOLOGICAL RESEARCH, 2023, 页码: 11
作者:
Chen, Ya-Ru
;
Yang, Hong-Jia
;
Cha, Jin-Myong
;
Zhang, Xin-Xin
;
Fan, Dong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/12/07
Beauveria bassiana
enzyme activity
Mythimna separata
RNA interference
serine protease inhibitor