中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [43]
大连化学物理研究所 [5]
昆明植物研究所 [5]
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Effect of Adulteration on Quality and Preliminary Risk Assessment of the Decoction Pieces of Farfarae Flos Based on the Determination of Hepatotoxic Pyrrolizidine Alkaloids by UHPLC-MS/MS
期刊论文
OAI收割
Journal of AOAC International, 2023, 卷号: 106, 期号: 1, 页码: 192-204
作者:
An-Ping Li
;
Shi YP(师彦平)
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/10/31
Comparative Pharmacokinetic Study of Two Pyrrolizidine Alkaloids Lasiocarpine and Heliotrine in Rats
期刊论文
OAI收割
PLANTA MEDICA, 2022, 页码: 9
作者:
Lin, Feifei
;
Zhao, Lijuan
;
Wang, Yingying
;
Ye, Yang
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/11/11
Lasiocarpine
Heliotrine
pyrrolizidine alkaloid
pharmacokinetics
Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12
作者:
Wang, Zhangting
;
Ma, Jiang
;
He, Yisheng
;
Miu, Kai-Kei
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2022/08/30
Pyrrolizidine alkaloids
Herb-induced liver injury
18 beta-glycyrrhetinic acid
Liquorice
Nuclear factor erythroid-2-related factor 2
PI3K/Akt/GSK3 beta
Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-alpha
期刊论文
OAI收割
TOXICOLOGY, 2022, 卷号: 468, 页码: 9
作者:
Cao, Yuhan
;
Liu, Meng
;
Wu, Shouyan
;
Xu, Junjiu
;
Wang, Wenjie
  |  
收藏
  |  
浏览/下载:19/0
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提交时间:2022/06/15
Monocrotaline
Kupffer cells
Necrosis
Hepatotoxicity
Dietary alcohol exacerbates the hepatotoxicity induced by pyrrolizidine alkaloids: Hazard from food contamination
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 424, 页码: 12
作者:
He, Yisheng
;
Long, Yun
;
Zhang, Chunyuan
;
Ma, Jiang
;
Ke, Changqiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/06/15
food contamination
pyrrolizidine alkaloids
alcohol
dietary exposure
mead
Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557
作者:
He, Yisheng
;
Zhang, Wei
;
Ma, Jiang
;
Xia, Qingsu
;
Song, Zijing
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/08/17
Simultaneous determination of monocrotaline and its N-oxide metabolite in rat plasma using LC-MS/MS: Application to a pharmacokinetic study
期刊论文
OAI收割
BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 7
作者:
Lin, Feifei
;
Pan, Anni
;
Ye, Yang
;
Liu, Jia
  |  
收藏
  |  
浏览/下载:51/0
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提交时间:2021/08/17
LC-MS
MS
monocrotaline
monocrotaline N-oxide
pharmacokinetics
Pyrrolizidine alkaloids from the seeds ofScleropyrum wallichianum
期刊论文
OAI收割
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 卷号: 23, 期号: 5, 页码: 407-413
作者:
Liu,Jun-Hong
;
Yang,Han
;
Zhang,Ling
;
Peng,Xing-Rong
;
Li,Zhen-Jie
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/04/02
Scleropyrum wallichianum
pyrrolizidine alkaloids
cytotoxicities
Metabolic Activation of Retrorsine may Disrupt Bile Acid Homeostasis in Mice through the Nrf2 Pathway
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 11, 页码: 870-881
作者:
Pang, Xiaoyan
;
Tang, Chongzhuang
;
Cao, Peng
;
Zhou, Lei
;
Chen, Xiaoyan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/06/15
Retrorsine
bile acid
oxidative stress
reactive metabolite
transporter
Nrf2
Pyrrolizidine alkaloids and unusual millingtojanine A-B from Jacobaea vulgaris (syn. Senecio jacobaea L.)
期刊论文
OAI收割
PHYTOCHEMISTRY, 2021, 卷号: 190, 期号: 10, 页码: 1-9
作者:
Jumai, A (Jumai, Aikebaier) 1 , 2 , 3
;
Rouzimaimaiti, R (Rouzimaimaiti, Ruxianguli) 1 , 2
;
Zou, GA (Zou, Guo-An) 1 , 2
;
Aisa, HA (Aisa, Haji Akber) 1 , 2 , 3
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2021/09/22
Jacobaea vulgaris Gaertn
Senecio
jacobaea
Tansy
ragwort
Asteraceae
pyrrolizidine alkaloids
Millingtojanine
X-ray diffraction analysis
ECD calculation