中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
水生生物研究所 [55]
上海药物研究所 [53]
海洋研究所 [14]
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期刊论文 [219]
学位论文 [8]
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Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/04/09
Programmable DNA hydrogel provides suitable microenvironment for enhancing autophagy-based therapies in intervertebral disc degeneration treatment
期刊论文
OAI收割
JOURNAL OF NANOBIOTECHNOLOGY, 2023, 卷号: 21
作者:
Qingxin, Song
;
Kai, Jiang
;
Dandan, Zheng
;
Linyu, Jin
;
Xiuyuan, Chen
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/10
Intervertebral disc degeneration
Gene therapy
DNA hydrogel
Autophagy
Extracellular matrix
Mitigation of Anti-Drug Antibody Production for Augmenting Anticancer Efficacy of Therapeutic Protein via Co-Injection of Nano-Rapamycin
期刊论文
OAI收割
SMALL, 2023, 页码: 12
作者:
Chang, Ya
;
Xiong, Wei
;
Zou, Chenming
;
Zeng, Ping
;
Hou, Jiazhen
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
anti-drug antibody
co-injection
immunological tolerance
rapamycin nanoparticles
trichosanthin
Effects of salinity training on growth performance, osmotic regulation, and pathogen resistance of post-larval Litopenaeus vannamei
期刊论文
OAI收割
AQUACULTURE, 2023, 卷号: 562, 页码: 10
作者:
Liu, Yuan
;
Wang, Baojie
;
Jiang, Keyong
;
Zhao, Zhiqun
;
Liu, Mei
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2023/01/06
Compensatory growth
mTOR signaling pathway
Salinity changes
Shrimp nursery farming
Targeting the PI3K/AKT/mTOR Signaling Pathway in the Treatment of Human Diseases: Current Status, Trends, and Solutions
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 29
作者:
Huang, Jindi
;
Chen, Liye
;
Wu, Jiangxia
;
Ai, Daiqiao
;
Zhang, Ji-Quan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates
期刊论文
OAI收割
CELLULAR AND MOLECULAR LIFE SCIENCES, 2022, 卷号: 79, 期号: 9
作者:
Pu, Mei
;
Tai, Yusi
;
Yuan, Luyang
;
Zhang, Yu
;
Guo, Huijie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/10/09
ALS
C9orf72
Poly-GA
Proteasome
Autophagy
The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates
期刊论文
OAI收割
CELLULAR AND MOLECULAR LIFE SCIENCES, 2022, 卷号: 79, 期号: 9, 页码: 23
作者:
Pu, Mei
;
Tai, Yusi
;
Yuan, Luyang
;
Zhang, Yu
;
Guo, Huijie
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/09/30
ALS
C9orf72
Poly-GA
Proteasome
Autophagy
New Evidence of Central Nervous System Damage in Diabetes: Impairment of Fine Visual Discrimination
期刊论文
OAI收割
DIABETES, 2022, 卷号: 71, 期号: 8, 页码: 1772-1784
作者:
Chen, He
;
Wang, Menghan
;
Xia, Lin
;
Dong, Jiong
;
Xu, Guangwei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/02/06
Targeting Glutamine Metabolism Ameliorates Autoimmune Hepatitis via Inhibiting T Cell Activation and Differentiation
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 13
作者:
Yu, Qiang
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
glutamine metabolism
autoimmune hepatitis (AIH)
T cells activation and differentiation
mTOR signaling
Natural scaffolds-inspired synthesis of CF3-substituted macrolides enabled by Rh-catalyzed C-H alkylation macrocyclization
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2022, 卷号: 33, 期号: 4, 页码: 2015-2020
作者:
Bi, Tongyu
;
Xu, Yi
;
Xu, Xin
;
Tang, Bixi
;
Yang, Qing
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/16
Rh-catalyzed
C-H alkylation
Late stage macrocyclization
DFT calculation
Anti-inflammation