机构

• 上海药物研究所 [17]
• 金属研究所 [1]
• 新疆理化技术研究所 [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2023 [1]
• 2022 [4]
• 2021 [1]
• 2019 [1]
• 2018 [3]
• 2017 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design, Synthesis, and Biological Evaluation of 2-Aminothiazole Derivatives as Novel Checkpoint Kinase 1 (CHK1) Inhibitors 期刊论文  OAI收割 CHEMMEDCHEM, 2023, 页码: 19 作者:  Deng, Minjie;  Wang, Peipei;  Long, Xiubing;  Xu, Gaoya;  Wang, Chang   |  收藏  |  浏览/下载：13/0  |  提交时间：2023/04/10 2-aminothiazole  CHK1 inhibitors  antiproliferation  hematologic malignancies  biological activity   Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12 作者:  Liu, Linyue;  Li, Chuanju;  Xie, Yong;  Zhang, Lei;  Chen, Yunfu   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 HBV  Capsid protein inhibitors  Pharmacophore hybrid  Scaffold hopping  HepAD38 cells   Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2022, 卷号: 66, 页码: 16 作者:  Chen, Zonglong;  Li, Jiayi;  Yang, Hong;  He, Yulong;  Shi, Qiongyu   |  收藏  |  浏览/下载：34/0  |  提交时间：2022/08/16 P300  Bromodomain inhibitors  CBP30  SBDD   Design, synthesis and biological evaluation of (R)-5-methylpyrrolidin-2-ones as p300 bromodomain inhibitors with Anti-Tumor activities in multiple tumor lines 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 124, 页码: 15 作者:  Liu, Ruiqi;  Yang, Hong;  Chen, Zonglong;  Zhou, Kaixin;  Shi, Qiongyu   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 Epigenetics  p300  CBP  Bromodomain inhibitors  CCS1477   Synthesis and Biological Activities of Dihydrooxazolo[5,4-d]- pyrrolo[1,2-a]pyrimidinones 期刊论文  OAI收割 CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2022, 卷号: 42, 期号: 2, 页码: 543-556 作者:  Zeng, Y (Zeng Yan) [1] , [2];  Nie, LF (Nie Lifei) [1];  Niu, C (Niu Chao) [1];  Mamatjan, A (Mamatjan Aytilla) [1] , [2];  Bozorov, K (Bozorov Khurshed) [1]   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/05/17 oxazopyrimidinone  synthesis  bioisosterism  anticancer activity  antimicrobial activity  structure-activity relationships (SARs)   Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14647-14663 作者:  Han, Xu;  Song, Ning;  Saidahmatov, Abdusaid;  Wang, Peipei;  Wang, Yong   |  收藏  |  浏览/下载：58/0  |  提交时间：2021/12/16 Design, synthesis, and biological evaluation of a new class of histone acetyltransferase p300 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 180, 页码: 171-190 作者:     |  收藏  |  浏览/下载：45/0  |  提交时间：2020/07/01 p300 inhibitors  Epigenetics  Structure-activity relationship  Sensitive tumor cell proliferation  C646   Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB2R Ligands 期刊论文  OAI收割 CHEMMEDCHEM, 2018, 卷号: 13, 期号: 22, 页码: 2455-2463 作者:  Qian, Hai-Yan;  Wang, Zhi-Long;  Chen, Li-Li;  Pan, You-Lu;  Xie, Xiao-Yu   |  收藏  |  浏览/下载：88/0  |  提交时间：2019/01/08 cannabinoids  CB1R  CB2R  heteroaryl pyrimidines  heteroaryl triazines  ligands   Aminobenzisoxazole compounds as agonists of alpha 7 nicotinic acetylcholine receptors: a patent evaluation (WO 2017027600) 期刊论文  OAI收割 EXPERT OPINION ON THERAPEUTIC PATENTS, 2018, 卷号: 28, 期号: 5, 页码: 429-436 作者:  He, Yang;  Shen, Jingshan   |  收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Nicotinic receptors  alpha 7 nAchR  cognition  agonists  allosteric modulators   Lead compound optimization strategy (6) - improving the plasma stability 期刊论文  OAI收割 Acta Pharmaceutica Sinica, 2018, 卷号: 53, 期号: 2, 页码: 192-201 作者:  Wu Xiaowei;  Wang Jiang;  Liu Hong   |  收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 plasma stability  structural modification  lead compound  bioisosterism