中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [965]
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Worm-like micelles facilitate the intestinal mucus diffusion and drug accumulation for enhancing colorectal cancer therapy
期刊论文
OAI收割
Chinese Chemical Letters, 2024, 卷号: 35, 期号: 6, 页码: 108967
作者:
Zhou, Yihan
;
Gao, Duo
;
Wang, Yaying
;
Liang, Li
;
Zhang, Qingyu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/03/26
Prevalence and risk factors for abnormal glucose metabolism in first-episode and drug-na?ve major depressive disorder outpatients with comorbid anxiety: A cross-sectional study from a large sample of the Chinese Han population
期刊论文
OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2024, 卷号: 349, 页码: 400-406
作者:
Xu, Huixue
;
Liu, Liyan
;
Yang, Qian
;
Wang, Xin
;
Li, Zejun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/03/25
Major depressive disorder
Glucose disturbances
First -episode drug-naive
Anxiety
Gender differences in prevalence and clinical correlates of anxiety in first-episode and drug-na?ve patients with major depressive disorder comorbid with metabolic syndrome
期刊论文
OAI收割
BMC PSYCHIATRY, 2024, 卷号: 24, 期号: 1, 页码: 8
作者:
Gao, Wenqi
;
Deng, Zhifang
;
Cai, Xiaonan
;
Zhang, Dan
;
Xiao, Han
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/15
Metabolic syndrome
Anxiety
First-episode and drug-naive major depressive disorder
Chinese han
Gender differences
Development of Potent MALT1 Inhibitors Featuring a Novel "2-Thioxo-2,3-dihydrothiazolo[4,5-
d
]pyrimidin-7(6
H
)-one" Scaffold for the Treatment of B Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2884-2906
作者:
Liang, Xuewu
;
Yu, Haolan
;
Liang, Renwen
;
Feng, Zhuanghui
;
Saidahmatov, Abdusaid
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/04/09
Regulating protein corona on nanovesicles by glycosylated polyhydroxy polymer modification for efficient drug delivery
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15, 期号: 1, 页码: 20
作者:
Miao, Yunqiu
;
Li, Lijun
;
Wang, Ying
;
Wang, Jiangyue
;
Zhou, Yihan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/03/13
Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17
作者:
Lan, Yaohan
;
Peng, Xia
;
Ji, Yinchun
;
Su, Yi
;
Duan, Wenhu
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/27
AXL inhibitor
In vivo antitumor efficacy
6-Naphthyridin-4-one derivatives
Scaffold hopping
Structure-based drug design
Intelligent design and construction of novel APN-based theranostic probe driven by advanced computational methods
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2024, 卷号: 35, 期号: 2, 页码: 6
作者:
Zhu, Yingli
;
Qian, Jie
;
Yu, Kunqian
;
Hou, Jing
;
Ma, Yeshuo
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/01/26
Theranostic probe
Artificial intelligence
Conformational restriction
Fluorescence restoration
Design strategy
pH-responsive nanogels with enhanced antioxidant and antitumor activities on drug delivery and smart drug release
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2024, 卷号: 257, 页码: 16
作者:
Ma, Bing
;
Li, Qing
;
Mi, Yingqi
;
Zhang, Jingjing
;
Tan, Wenqiang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
Benzimidazole-chitosan quaternary ammonium
salt
Nanogels
pH-responsive
Antioxidant activity
Antitumor activity
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Discovery, Optimization, and Evaluation of Novel Pyridin-2(1
H
)-one Analogues as Potent TRK Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183
作者:
Xu, Zichao
;
Peng, Xia
;
Zhang, Renjie
;
Ji, Yinchun
;
You, Mengke
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27