中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共109条,第1-10条 帮助

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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:  
Hao, Bing-bing;  Ma, Ke;  Xu, Jun-yu;  Fan, Ru-feng;  Zhao, Wen-si
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/03/25
NIR-II fluorescence-guided liver cancer surgery by a small molecular HDAC6 targeting probe 期刊论文  OAI收割
EBIOMEDICINE, 2023, 卷号: 98, 页码: 18
作者:  
Wang, Bo;  Tang, Chu;  Lin, En;  Jia, Xiaohua;  Xie, Ganyuan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2024/02/22
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:  
Wang, Xiaomin;  Xu, Jun;  Sun, Yiming;  Cao, Siyuwei;  Zeng, Hanlin
  |  收藏  |  浏览/下载:23/0  |  提交时间:2023/10/17
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:  
Li, Daqiang;  Zhang, Zhuo;  Li, Yalei;  Wang, Xinyi;  Zhong, Hanyue
  |  收藏  |  浏览/下载:17/0  |  提交时间:2023/10/17
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文  OAI收割
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:  
Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun
  |  收藏  |  浏览/下载:19/0  |  提交时间:2022/11/21
Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation 期刊论文  OAI收割
GENOMICS PROTEOMICS & BIOINFORMATICS, 2022, 卷号: 20, 期号: 4, 页码: 597-613
作者:  
Jiang, Yuejing;  Cong, Xiaoji;  Jiang, Shangwen;  Dong, Ying;  Zhao, Lei
  |  收藏  |  浏览/下载:14/0  |  提交时间:2023/04/10

A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo

期刊论文  OAI收割

BIOCHEMICAL PHARMACOLOGY, 2022, 卷号: 201, 页码: 12
作者:  
Li, Yin-Ru;  Liu, Fang-Fang;  Liu, Wen-Bo;  Zhang, Yi-Fan;  Tian, Xin-Yi
  |  收藏  |  浏览/下载:23/0  |  提交时间:2022/08/16
A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo 期刊论文  OAI收割
BIOCHEMICAL PHARMACOLOGY, 2022, 卷号: 201, 页码: 115070
作者:  
Li, Yin-Ru;  Liu, Fang-Fang;  Liu, Wen-Bo;  Zhang, Yi-Fan;  Tian, Xin-Yi
  |  收藏  |  浏览/下载:10/0  |  提交时间:2024/03/21
An Integrative Proteome-Based Pharmacologic Characterization and Therapeutic Strategy Exploration of SAHA in Solid Malignancies br 期刊论文  OAI收割
JOURNAL OF PROTEOME RESEARCH, 2022, 卷号: 21, 期号: 4, 页码: 953-964
作者:  
Liu, Quan;  Hao, Bingbing;  Zhang, Mingya;  Liu, Zhiwei;  Huang, Yuqi
  |  收藏  |  浏览/下载:30/0  |  提交时间:2022/06/15
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A(2A) Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 22, 页码: 16573-16597
作者:  
Yan, Wenzhong;  Ling, Lijun;  Wu, Yiran;  Yang, Kexin;  Liu, Ruiquan
  |  收藏  |  浏览/下载:16/0  |  提交时间:2022/06/15