中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [70]
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
HDAC3 and HDAC8 PROTAC dual degrader reveals roles of histone acetylation in gene regulation
期刊论文
OAI收割
CELL CHEMICAL BIOLOGY, 2023, 卷号: 30, 期号: 11, 页码: 1421-+
作者:
Xiao, Yufeng
;
Hale, Seth
;
Awasthee, Nikee
;
Meng, Chengcheng
;
Zhang, Xuan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/16
Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 118, 页码: 11
作者:
Yang, Shuangshuang
;
Fan, Lei
;
Zhang, Rui
;
Song, Chenghuan
;
Shi, Jiyun
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Alzheimer's disease
Brain-derived neurotrophic factor
Histone acetylation
Smilagenin
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Histone deacetylase inhibitors promote breast cancer metastasis by elevating NEDD9 expression
期刊论文
OAI收割
Signal Transduction and Targeted Therapy, 2023, 卷号: 8, 期号: 2, 页码: 692-704
作者:
Hu, Zonglong
;
Wei, Fan
;
Su, Yi
;
Wang, Yafang
;
Shen, Yanyan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/27
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
OAI收割
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
A dynamic fluorescence probed glycolysis suppression process in HeLa cells treated with trichostatin A
期刊论文
OAI收割
ANALYST, 2022
作者:
Zhang, Fengqiu
;
Shao, Changsheng
;
Wu, Yahui
;
Zhao, Wei
;
Jing, Xumiao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/12/22
A near-infrared fluorescent probe was used to evaluate the role of histone deacetylase in pulmonary fibrosis cells and mice
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2022, 卷号: 366, 页码: 8
作者:
Wei, Yinghui
;
Hou, Junjun
;
Lu, Pengpeng
;
Fu, Lili
;
Wang, Xiaoyan
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/07/26
Fluorescent probe
Near-infrared
Histone deacetylases
Idiopathic pulmonary fibrosis
Fluorescence imaging
A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2022, 卷号: 201, 页码: 115070
作者:
Li, Yin-Ru
;
Liu, Fang-Fang
;
Liu, Wen-Bo
;
Zhang, Yi-Fan
;
Tian, Xin-Yi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
Epigenetic regulation
Tubulin
HDAC
Anticancer activity