中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [8]
上海药物研究所 [7]
半导体研究所 [3]
化学研究所 [2]
南海海洋研究所 [1]
水生生物研究所 [1]
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OAI收割 [24]
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期刊论文 [22]
会议论文 [1]
学位论文 [1]
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2023 [1]
2022 [1]
2020 [1]
2019 [1]
2018 [2]
2017 [2]
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半导体物理 [2]
Analytical [1]
Chemistry [1]
半导体材料 [1]
物理化学 [1]
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Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone
期刊论文
OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490
作者:
Zhang, Shaoqing
;
Chen, Yue
;
Xu, Zhongli
;
Yang, Jun
;
Sun, Renhong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/04/10
Hedgehog
Bcl-xL
PROTAC
drug resistance
bone growth
岩藻糖化糖胺聚糖的寡糖结构及其抗乙酰肝素酶活性研究
学位论文
OAI收割
2020
作者:
周路坦
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2023/11/02
Discovery of a novel protein kinase C activator from Croton tiglium for inhibition of non-small cell lung cancer
期刊论文
OAI收割
PHYTOMEDICINE, 2019, 卷号: 65, 页码: 11
作者:
Wang Yuwei
;
Tang Chunping
;
Yao Sheng
;
Lai Huanling
;
Li Runze
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
Natural product
Croton tiglium
Protein kinase C
Molecular modelling
Novel substituted pyrazolone derivatives as AMP-activated protein kinase activators to inhibit lipid synthesis and reduce lipid accumulation in ob/ob mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 10, 页码: 1622-1632
作者:
Zhang, Mei
;
Xie, Zhi-fu
;
Zhang, Run-tao
;
Chen, Da-kai
;
Gu, Min
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/01/08
non-alcoholic fatty liver disease
AMP-activated protein kinase
AMPK activator
homogeneous time-resolved fluorescence
metabolic disorders
ob/ob mice
Spirostaphylotrichin X from a Marine-Derived Fungus as an Anti-influenza Agent Targeting RNA Polymerase PB2
期刊论文
OAI收割
JOURNAL OF NATURAL PRODUCTS, 2018, 卷号: 81, 期号: 12, 页码: 2722, 2730
作者:
Wang, Jianjiao
;
Liu, Yuxuan
;
Li, Kunlong
;
Yang, Xiliang
;
Liu, Shuwen
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/09/09
Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase
期刊论文
OAI收割
CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278
作者:
Dai, Xiaoyang
;
Yan, Juan
;
Fu, Xuhong
;
Pan, Qiuming
;
Sun, Danni
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
The Laser-Induced Fluorescence Spectrum of Jet-Cooled Diatomic Sulfur in Ultraviolet Region
期刊论文
OAI收割
SPECTROSCOPY AND SPECTRAL ANALYSIS, 2017, 卷号: 37, 页码: 2792-2798
作者:
Ma Xin-wen
;
Wang Shu-long
;
Xiang Qian-lan
;
Zhao Dong-mei
;
Yang Jie
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2018/05/31
Diatomic sulfur molecule
Laser-induced fluorescence spectroscopy
Low energy excited state
Electronic state structure
Homogeneous perturbation
Discovery of New Non-Steroidal Farnesoid X Receptor Modulators Through 3D Shape Similarity Search and Structure-Based Virtual Screening
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 85, 期号: 4, 页码: 481-487
作者:
Wang, Lei
;
Si, Pei
;
Sheng, Yayun
;
Chen, Yingjie
;
Wan, Ping
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
farnesoid X receptor
modulators
similarity search
virtual screening
Identification of a Novel Small-Molecule Agonist for Human G Protein-Coupled Receptor 3
期刊论文
OAI收割
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2014, 卷号: 349, 期号: 3, 页码: 437-443
作者:
Ye, Chenli
;
Zhang, Zhenghong
;
Wang, Zhilong
;
Hua, Qiuhong
;
Zhang, Ru
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08