中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [126]
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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 125, 页码: 15
作者:
Feng, Qilin
;
Hu, Ke
;
Hu, Huifang
;
Lu, Yumeng
;
Zhang, Hui
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2024/01/16
DLBCL
ROS
DNA damage
JNK
Mitochondrial dysfunction
Treating relapsed/refractory mature T- and NK-cell neoplasms with tislelizumab: a multicenter open-label phase 2 study
期刊论文
OAI收割
BLOOD ADVANCES, 2023, 卷号: 7
作者:
Bachy, Emmanuel
;
Savage, Kerry J.
;
Huang, Huiqiang
;
Kwong, Yok-Lam
;
Gritti, Giuseppe
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/11/10
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:
Chen, Yun
;
Ning, Yi
;
Chen, Zhiwei
;
Xue, Yaping
;
Wu, Qingyun
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
Apoptosis
Diffuse large B-Cell lymphoma
Interleukin-1 receptor associated kinase 4
Structure-based drug design
2
3-Dihydrobenzofuran
Novel thieno[2,3-b]quinoline-procaine hybrid molecules: A new class of allosteric SHP-1 activators evolved from PTP1B inhibitors
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 8, 页码: 6
作者:
Xu, Lei
;
Xuyan, Xuyang
;
Minmi, Minmin
;
Wang, Zhiji
;
Shee, Chao
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/10/17
Activator
PTPs
Inhibitor
Thieno[2
b ]quinoline derivatives
Diffuse large B-cell lymphoma
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Guo, Cheng-cen
;
Xu, H. Eric
;
Ma, Xiong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
transcription factors
ARID
ARID3a
autoimmune diseases
systemic lupus erythematosus
primary biliary cholangitis
Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Yu, Lei
;
Wang, Ya-fang
;
Xiao, Jian
;
Shen, Qian-qian
;
Chi, Shuai-shuai
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/10/17
diffuse large B-cell lymphoma
EZH2
TfR-1
GPX4
ferroptosis
HH2853
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644
作者:
Zhang, Yi
;
Yang, Hong
;
Li, Bingbing
;
Li, Jiayi
;
Li, Huaxuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
Cocrystal Prediction of Bexarotene by Graph Convolution Network and Bioavailability Improvement
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 10, 页码: 19
作者:
Xiao, Fu
;
Cheng, Yinxiang
;
Wang, Jian-Rong
;
Wang, Dingyan
;
Zhang, Yuanyuan
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/12/13
bexarotene
cocrystal prediction
GCN
bioavailability