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Discovery and Optimization of Tetrahydroisoquinoline Derivatives To Enhance Lysosome Biogenesis as Preclinical Candidates for the Treatment of Alzheimer's Disease
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 11, 页码: 8836-8861
Authors:
Zhou, Jianhui
;
Wang, Ning
;
Wang, Mengxue
;
Hu, Yuting
;
Zhang, Zhenwei
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View/Download:19/0
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Submit date:2024/07/12
Functional analyses of TRAF6 gene in Argopecten scallops
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2024, 卷号: 147, 页码: 9
Authors:
Zhang, Xiaotong
;
Wang, Xia
;
Chen, Jieyu
;
Chen, Min
;
Lu, Xia
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View/Download:7/0
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Submit date:2024/05/07
Argopecten irradians (Air)
Argopecten purpuratus (Apu)
Tumor necrosis factor (TNF)
TNF receptor-associated factor (TRAF)
Subcellular localization
RNA interference (RNAi)
eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 5, 页码: 14
Authors:
Luo, Jichang
;
Zhang, Xiao
;
Li, Wenjing
;
Wang, Tao
;
Cui, Shengyan
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View/Download:24/0
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Submit date:2024/07/03
Carotid artery atherosclerosis
Primary vascular smooth muscle cells
Organelles
Plaque vulnerability
Translation initiation factor 2 alpha
Integrated analysis of a miRNA-mRNA network related to immunity and autophagy in Macrobrachium rosenbergii infected with Aeromonas hydrophila
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 141, 页码: 11
Authors:
Wang, Feifei
;
Zhao, Fei
;
Tan, Aiping
;
Deng, Yuting
;
Wang, Ling
  |  
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  |  
View/Download:16/0
  |  
Submit date:2023/11/30
Macrobrachium rosenbergii
miRNA-mRNA
Immunity
Autophagy
Aeromonas hydrophila
Molecular mechanism by which RRM2-inhibitor (cholagogue osalmid) plus bafilomycin A1 cause autophagic cell death in multiple myeloma
期刊论文
OAI收割
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2023, 卷号: 747, 页码: 12
Authors:
Guo, Shushan
;
Xu, Zhijian
;
Feng, Qilin
;
Zhang, Hui
;
Yu, Dandan
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  |  
View/Download:16/0
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Submit date:2023/12/11
Autophagy
RRM2
p62
RIPK3
Cholagogue osalmid
Bafilomycin A1
Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17
Authors:
Zeng, Yanping
;
Xiao, Jian
;
Xu, Yuanxin
;
Wei, Fan
;
Tian, Lina
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View/Download:12/0
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Submit date:2023/10/17
The in vivo drug delivery pattern of the organelle-targeting small molecules
期刊论文
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ADVANCED DRUG DELIVERY REVIEWS, 2023, 卷号: 200, 页码: 14
Authors:
Fang, Zhao
;
Chen, Hao
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  |  
View/Download:13/0
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Submit date:2023/10/17
Organelle-targeting
In vivo imaging
Small molecular probe
Biodistribution
Subcellular structure
Human disease
The lysosome-phagosome pathway mediates immune regulatory mechanisms in Mesocentrotus nudus against Vibrio coralliilyticus infection
期刊论文
OAI收割
FISH & SHELLFISH IMMUNOLOGY, 2023, 卷号: 139, 页码: 13
Authors:
Wang, Yanxia
;
Wang, Quanchao
;
Chen, Linlin
;
Li, Baoquan
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  |  
View/Download:13/0
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Submit date:2024/01/26
Mesocentrotusnudus
Lysosome
Phagosome
Vibrio coralliilyticus
V-ATPases
Cellular proteins act as surfactants to control the interfacial behavior and function of biological condensates
期刊论文
OAI收割
DEVELOPMENTAL CELL, 2023, 卷号: 58, 期号: 11, 页码: 919
Authors:
Wang, Zheng
;
Yang, Chun
;
Guan DS(关东石)
;
Li, Jiaqi
;
Zhang, Hong
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View/Download:14/0
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Submit date:2023/07/17
Characterization of the role of TMEM175 in an in vitro lysosomal H+ fluxes model
期刊论文
OAI收割
FEBS JOURNAL, 2023, 页码: 19
Authors:
Yang, Chuanyan
;
Tian, Fuyun
;
Hu, Mei
;
Kang, Chunlan
;
Ping, Meixuan
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View/Download:65/0
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Submit date:2023/10/17
glycocalyx
H+ leak
lysosome acidification
proton channel
TMEM175