机构

• 上海药物研究所 [21]
• 上海营养与健康研究... [12]
• 大连化学物理研究所 [4]
• 昆明植物研究所 [4]
• 上海生物化学与细胞生... [4]
• 合肥物质科学研究院 [4]
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采集方式

• OAI收割 [62]
• iSwitch采集 [2]

内容类型

• 期刊论文 [60]
• 学位论文 [4]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [5]
• 2020 [4]
• 2019 [8]
• 2018 [11]
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学科主题

• Cell Biolo... [9]
• Biochemist... [1]
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• Genetics &... [1]
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筛选

浏览/检索结果: 共64条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15 作者:  Mei, Lianghe;  Xu, Lansong;  Wu, Sanan;  Wang, Yafang;  Xu, Chao   |  收藏  |  浏览/下载：39/0  |  提交时间：2023/10/17 Betulinic acid  ROR & gamma  Target identification  Rationale structure optimization  Anti-tumor effects  antagonists   Xanthine dehydrogenase rewires metabolism and the survival of nutrient deprived lung adenocarcinoma cells by facilitating UPR and autophagic degradation 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 卷号: 19, 期号: 3, 页码: 772-788 作者:  Chen, Man-man;  Guo, Wei;  Chen, Si-meng;  Guo, Xiao-zhen;  Xu, Lan   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 Xanthine dehydrogenase  nucleoside degradation  cell survival  UPR  autophagy  LUAD   Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14 作者:  Huang, Su-Ling;  Xie, Wei;  Ye, Yang-Liang;  Liu, Jia;  Qu, Hui   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/11/11 type 2 diabetes mellitus  coronarin A  glycogen synthesis  gluconeogenesis  mTORC1  IRS1   SAF-248,a novel PI3Kδ-selective inhibitor,potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 209 作者:  Zhang Xi;  Duan Yuting;  Wang Yi;  Zhao Xingdong;  Sun Yiming   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/05/22 PI3K6  PI3K/AKT/mTOR  diffuse large B-cell lymphoma  resistance  combination therapy   Role of Borneol Induced Autophagy in Enhancing Radiosensitivity of Malignant Glioma 期刊论文  OAI收割 FRONTIERS IN ONCOLOGY, 2021, 卷号: 11 作者:  Li, Qinglin;  Xia, Liang;  Sun, Caixing;  Zhang, Huangjie;  Zheng, Mengying   |  收藏  |  浏览/下载：56/0  |  提交时间：2022/01/25 natural product  borneol  malignant glioma  autophagy  HIF-1 alpha   SAF-248, a novel PI3K delta-selective inhibitor, potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Xi;  Duan, Yu-ting;  Wang, Yi;  Zhao, Xing-dong;  Sun, Yi-ming   |  收藏  |  浏览/下载：52/0  |  提交时间：2021/05/24 PI3Kδ  PI3K  AKT  mTOR  diffuse large B-cell lymphoma  resistance  combination therapy   Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells 期刊论文  OAI收割 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13 作者:  Wang, Yu-xiang;  Zhang, Xu;  Ma, Qing-yang;  Hu, Lan-dian;  Zhang, Xi   |  收藏  |  浏览/下载：42/0  |  提交时间：2021/05/24 A novel silicone derivative of natural osalmid (DCZ0858) exerts anti-multiple myeloma activity by promoting cell apoptosis and inhibiting cell cycle and mTOR signaling 期刊论文  OAI收割 AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH, 2021, 卷号: 13, 期号: 10, 页码: 11439-11449 作者:  Bu, Wenxuan;  Li, Bo;  Feng, Lijin;  Feng, Qilin;  Hu, Ke   |  收藏  |  浏览/下载：20/0  |  提交时间：2021/12/16 Multiple myeloma  DCZ0858  mTOR  bone marrow microenvironment  cell proliferation  cell apoptosis   The Development and Survival of Thymic Epithelial Cells Require TSC1-Dependent Negative Regulation of mTORC1 Activity 期刊论文  OAI收割 JOURNAL OF IMMUNOLOGY, 2021, 卷号: 207, 期号: 8, 页码: 2039-2050 作者:  Liang Zhanfeng;  Zhang Qian;  Zhang Zhaoqi;  Sun Lina;  Dong Xue   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/04/17 醋酸棉酚调控细胞自噬发挥抗肿瘤作用的机制研究 学位论文  OAI收割 2020 作者:  蔡碧宬   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/11/02