中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [33]
上海应用物理研究所 [4]
武汉物理与数学研究所 [2]
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OAI收割 [43]
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期刊论文 [38]
项目 [4]
学位论文 [1]
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Nanobodies as negative allosteric modulators for human calcium sensing receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2024, 卷号: 695, 页码: 9
作者:
Cui, Qianqian
;
Wang, Lu
;
Wang, Haonan
;
Chen, Xiaochen
;
Han, Li
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/04/09
G-protein-coupled receptor
Extracellular calcium sensing receptor
Nanobody
Cryo-electron microscope
Systemic Ca 2+homoeostasis
C-terminal modification and functionalization of proteins via a self-cleavage tag triggered by a small molecule
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 13
作者:
Zeng, Yue
;
Shi, Wei
;
Liu, Zhi
;
Xu, Hao
;
Liu, Liya
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/02/19
Structure basis of two nanobodies neutralizing SARS-CoV-2 Omicron variant by targeting ultra-conservative epitopes
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 3, 页码: 9
作者:
Sun, Zengchao
;
Wang, Lu
;
Li, Lingyun
;
Sun, Yili
;
Zhang, Daizhou
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
SARS-CoV-2 virus
Receptor -binding domain
Nanobody
Crystal structure
Conservative binding epitope
Bi-paratopic nanobodies
Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3Ka)
期刊论文
OAI收割
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023, 卷号: 1878, 期号: 5, 页码: 6
作者:
Vogt, Peter K.
;
Hart, Jonathan R.
;
Yang, Su
;
Zhou, Qingtong
;
Yang, Dehua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
Phosphoinositide 3-kinase
BYL-719
Nanobody
CXMS
Mutants
Preparation and characterization of nanobodies targeting SARS-CoV-2 papain-like protease
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106267
作者:
Qiao, Huarui
;
Li, Lingyun
;
Wang, Lu
;
Yu, Haijun
;
Hu, Fangzheng
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/27
SARS-CoV-2
Papain like protease (PLpro)
Nanobody
PLpro inhibitor
A procedure for producing an anti-AXL nanobody in E. coli
期刊论文
OAI收割
PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268
作者:
Lan, Zhongyun
;
Li, Lingyun
;
Sun, Yili
;
Meng, Xiangjing
;
Shi, Zhenzhong
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/27
AXL
Nanobody
Expression
Purification
Sensitivity-enhanced nanoplasmonic biosensor using direct immobilization of two engineered nanobodies for SARS-CoV-2 spike receptor-binding domain detection
期刊论文
OAI收割
SENSORS AND ACTUATORS B-CHEMICAL, 2023, 卷号: 383, 页码: 133575
作者:
Ma, Zhengtai
;
Sun, Zengchao
;
Lv, Xiaoqing
;
Chen, Hongda
;
Geng, Yong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/03/27
Nanoplasmonics
Biosensor
COVID-19
Nanobody
Immobilization
High -throughput
Construction of stable membranal CMTM6-PD-L1 full-length complex to evaluate the PD-1/PD-L1-CMTM6 interaction and develop anti-tumor anti-CMTM6 nanobody
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 10
作者:
Jia, Xiao-min
;
Long, Yi-ru
;
Yu, Xiao-lu
;
Chen, Run-qiu
;
Gong, Li-kun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/04/10
cancer immunotherapy
CMTM6
CMTM6
PD-L1 complex
protein interactions
anti-CMTM6 nanobody
PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way
期刊论文
OAI收割
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 10, 页码: 15
作者:
Yu, Xiaolu
;
Long, Yiru
;
Chen, Binfan
;
Tong, Yongliang
;
Shan, Mengwen
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/13
PD-L1
TLR7
nanobody-drug-conjugate
cancer immunotherapy
Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9
作者:
Hart, Jonathan R.
;
Liu, Xiao
;
Pan, Chen
;
Liang, Anyi
;
Ueno, Lynn
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
phosphoinositide 3-kinase (PI3K)
nanobody
conformational changes
chemical cross-linking
mass spectrometry