机构

• 上海药物研究所 [28]
• 植物研究所 [14]
• 上海生物化学与细胞生... [9]
• 中国科学院大学 [8]
• 上海神经科学研究所 [7]
• 武汉病毒研究所 [7]
• 更多

采集方式

• OAI收割 [103]
• iSwitch采集 [15]

内容类型

• 期刊论文 [114]
• 学位论文 [4]

发表日期

• 2023 [7]
• 2022 [10]
• 2021 [5]
• 2020 [9]
• 2019 [7]
• 2018 [5]
• 更多

学科主题

• Biochemis... [11]
• Plant Scie... [9]
• Cell Biolo... [5]
• Neuroscien... [4]
• Genetics &... [3]
• Biochemist... [2]
• 更多

筛选

浏览/检索结果: 共118条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 4, 页码: 2466-2486 作者:  Chang, Qi;  Li, Jiayi;  Deng, Yue;  Zhou, Ruilin;  Wang, Bingwei   |  收藏  |  浏览/下载：11/0  |  提交时间：2024/03/25 Dihydrocelastrol induces antitumor activity and enhances the sensitivity of bortezomib in resistant multiple myeloma by inhibiting STAT3-dependent PSMB5 regulation 期刊论文  OAI收割 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 12, 页码: 1884-1891 作者:  Jin, Shuhan;  Li, Bo;  Zhang, Bibo;  Gao, Xuejie;  Jia, Xinyan   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/02/27 dihydrocelastrol  multiple myeloma  JAK2/STAT3  PSMB5  bortezomib resistance   The new direction of drug development: Degradation of undruggable targets through targeting chimera technology 期刊论文  OAI收割 MEDICINAL RESEARCH REVIEWS, 2023, 页码: 54 作者:  Liang, Xuewu;  Ren, Hairu;  Han, Fengyang;  Liang, Renwen;  Zhao, Jiayan   |  收藏  |  浏览/下载：20/0  |  提交时间：2024/01/16 chimeric design  degradation System  PROTAC  targeted degradation technology  undruggable targets   Degradation of Cyclin-Dependent Kinase 9/Cyclin T1 by Optimized Microtubule-Associated Protein 1 Light Chain 3 Beta-Recruiting Coumarin Analogs 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 17 作者:  Zeng, Yanping;  Xiao, Jian;  Xu, Yuanxin;  Wei, Fan;  Tian, Lina   |  收藏  |  浏览/下载：7/0  |  提交时间：2023/10/17 Structure-based discovery of potent USP28 inhibitors derived from Vismodegib 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15 作者:  Zhou, Di;  Xu, Zhuo;  Huang, Yaodong;  Wang, Hui;  Zhu, Xiaoli   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 USP28  Structure-based  Vismodegib derivatives  Structure-activity relationships  c-Myc   Stimuli-activatable PROTACs for precise protein degradation and cancer therapy 期刊论文  OAI收割 SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085 作者:  Gao, Jing;  Yang, Lei;  Lei, Shumin;  Zhou, Feng;  Nie, Huijun   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/10/17 PROTAC  Stimuli-activatable prodrug  Precise protein degradation  Nanomedicine  Combinatory therapy   An endoplasmic reticulum-associated degradation-related E2-E3 enzyme pair controls grain size and weight through the brassinosteroid signaling pathway in rice 期刊论文  OAI收割 PLANT CELL, 2023, 卷号: 35, 期号: 3, 页码: 1076-1091 作者:  Li, Jing;  Zhang, Baolan;  Duan, Penggen;  Yan, Li;  Yu, Haiyue   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/07 Global ubiquitinome analysis reveals the role of E3 ubiquitin ligase FaBRIZ in strawberry fruit ripening 期刊论文  OAI收割 JOURNAL OF EXPERIMENTAL BOTANY, 2023, 卷号: 74, 期号: 1, 页码: 214-232 作者:  Wang, Yuying;  Kong, Lingxi;  Wang, Weihao;  Qin, Guozheng   |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/07 Fruit ripening  protein post-translational modification  strawberry  ubiquitination  ubiquitinome  ubiquitin-proteasome system (UPS)   Development of a novel PROTAC using the nucleic acid aptamer as a targeting ligand for tumor selective degradation of nucleolin 期刊论文  OAI收割 MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 卷号: 30 作者:  Zhang, Lin;  Li, Ling;  Wang, Xia;  Liu, Huimin;  Zhang, Yibin   |  收藏  |  浏览/下载：35/0  |  提交时间：2022/12/23 Discovery of Highly Potent Nicotinamide Phosphoribosyltransferase Degraders for Efficient Treatment of Ovarian Cancer 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Bi, Kaijian;  Cheng, Junfei;  He, Shipeng;  Fang, Yuxin;  Huang, Min   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10